530103-18-5Relevant academic research and scientific papers
EDC-mediated condensations of 1-chloro-5-hydrazino-9,10-anthracenedione, 1-hydrazino-9,10-anthracenedione, and the corresponding anthrapyrazoles
Kim, MeeKyoung,Wiemer, David F.
, p. 4977 - 4980 (2004)
The EDC-mediated condensation of 1-chloro-5-hydrazino-9,10-anthracenedione afforded an N-1 acyl anthrapyrazole instead of the expected hydrazide. The regiochemistry of the N-acyl substituent was assigned on the basis of an extensive set of NMR experiments, and identification of this isomer suggests a reaction sequence based on initial acylation and subsequent cyclization. In contrast, the parallel reaction of 1-hydrazino-9,10-anthracenedione proceeded to afford the expected hydrazide.
Tripeptide probes for tripeptidyl protease I production via gene transfer
Kim, MeeKyoung,Mao, Qinwen,Davidson, Beverly L.,Wiemer, David F.
, p. 1603 - 1608 (2007/10/03)
Tripeptides derived from 5-chloroanthraquinone hydrazide and anthraquinone hydrazide have been prepared as potential reagents to probe cellular expression of tripeptidyl protease I (TPP-I). Attempted chemical synthesis of Gly-L-Pro-L-Ala-chloroanthraquino
