530116-20-2Relevant academic research and scientific papers
An efficient: T -BuOK promoted C3-chalcogenylation of indoles with dichalcogenides
Yu, Yuanzu,Zhou, Yan,Song, Zengqiang,Liang, Guang
, p. 4958 - 4962 (2018)
A versatile and efficient method for the synthesis of 3-chalcogenyl-indoles from indoles and dichalcogenides employing t-BuOK as a promoter at room temperature has been achieved. The present protocol exhibited a broad functional group tolerance. Diverse 3-sulfenyl- and 3-selenyl-indoles were rapidly obtained in good to excellent yields with high regioselectivities. It is noteworthy that this transformation was applicable to N-protected and N-unprotected indoles, allowing N-deprotection and C3-chalcogenylation of indoles in one step.
A metal-free sulfenylation and bromosulfenylation of indoles: Controllable synthesis of 3-arylthioindoles and 2-bromo-3-arylthioindoles
Huang, Dayun,Chen, Jiuxi,Dan, Weixing,Ding, Jinchang,Liu, Miaochang,Wu, Huayue
, p. 2123 - 2128 (2012/11/06)
An efficient metal-free sulfenylation of indoles with disulfides has been developed, leading to 3-arylthioindoles in moderate to excellent yields. Furthermore, bromosulfenylation of indoles with disulfides has been realized for the first time providing a
CANNABINOID RECEPTOR LIGANDS
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Page/Page column 73-74, (2008/06/13)
Compounds of Formula (I) and/or pharmaceutically acceptable salts, solvates or prodrugs thereof, or pharmaceutical compositions containing such compounds exhibit anti-inflammatory and immunomodulatory activity, and can be effective asCB2 receptor ligands in treating cancer and inflammatory, immunomodulatory or respiratory diseases or conditions.
CANNABINOID RECEPTOR LIGANDS
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Page/Page column 58-59, (2010/02/05)
There are disclosed compounds of the formula I: or a pharmaceutically acceptable salt of the compound, which exhibit anti-inflammatory and immunomodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds.
