530145-21-2

Basic information

• Product Name: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate
• Synonyms: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate
• CAS NO: 530145-21-2
• Molecular Weight: 284.312
• Mol File: 530145-21-2.mol

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate(530145-21-2)
• EPA Substance Registry System: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate(530145-21-2)

Safety Data

• Hazardous Substances Data: 530145-21-2(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 100-51-6 benzyl alcohol 
• 18153-53-2 methyl 4-(N,N-dimethylaminomethyl)benzoate 

Downstream Products

• 22744-12-3 [4-(methoxycarbonyl)phenyl]acetic acid 
• 1354804-45-7 4-{2-[9-(3-fluorobenzyl)-5,6,8,9-tetrahydro-7H-pyrido[4',3':4,5]pyrrolo[2,3-b]pyridin-7-yl]-2-oxoethyl}benzoic acid 

Relevant articles and documents

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF

A benzophenone derivative represented by the following formula: whereinR1 represents, for example, an optionally substituted heterocyclic group, or a substituted phenyl group; Z represents, for example, an alkylene group; R2 represents, for example, a carboxyl group optionally protected with alkyl;R3 represents, for example, an optionally protected hydroxyl group; R4 represents, for example, an optionally substituted cycloalkyloxy group; and R5 represents, for example, a hydrogen atom, ???or a salt thereof has anti-arthritic activity, inhibits bone destruction caused by arthritis, and provides high safety and excellent pharmacokinetics and thus is useful as therapeutic agent for arthritis. These compounds have inhibitory effect on AP-1 activity and are useful as preventive or therapeutic agent for diseases in which excessive expression of AP-1 is involved.