5302-80-7

Basic information

• Product Name: 2-{[5-(4-chlorophenyl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3,4-difluorophenyl)acetamide
• CAS NO: 5302-80-7
• Molecular Formula: C₂₁H₁₅ClF₂N₄O₂S
• Molecular Weight: 460.8842
• Mol File: 5302-80-7.mol
• Article Data: 1

Chemical Properties

• Density: 1.46g/cm³
• Refractive Index: 1.663
• CAS DataBase Reference: 2-{[5-(4-chlorophenyl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3,4-difluorophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[5-(4-chlorophenyl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3,4-difluorophenyl)acetamide(5302-80-7)
• EPA Substance Registry System: 2-{[5-(4-chlorophenyl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3,4-difluorophenyl)acetamide(5302-80-7)

Safety Data

• Hazardous Substances Data: 5302-80-7(Hazardous Substances Data)

Relevant articles and documents

PREPARATION OF D-GLUCOSE AND D-GLUCOSE

An enzymic method is presented for the preparation of 14C-labelled and C1-deuterated D-glucose, to be used as a radioactive tracer in metabolic studies dealing with the fate of D-glucose.The procedure takes advantage of the deuteration of 14C-labelled D-fructose 6-phosphate during exposure to phosphomannoisomerase in D2O.It further includes the conversion of the deuterated hexose monophosphates to D-fructose 1,6-bisphosphate, its isolation and hydrolysis to D-fructose 6-phosphate and the partial conversion of the latter ester to D-glucose 6-phosphate, which is then isolated by ion exchange chromatography and hydrolyzed to unesterified D-glucose.The extent of deuteration on the C1 of D-glucose was judged, after conversion to D-glucose 6-phosphate, from the isotopic discrimination in reaction velocity exerted towards the C1-deuterated ester by glucose-6-phosphate dehydrogenase.The degree of isotopic discrimination was virtually identical to that found with D-glucose 6-phosphate prepared from pure D-glucose.