53045-66-2Relevant articles and documents
Catalytic Regiodivergent Kinetic Resolution of Allylic Epoxides: A New Entry to Allylic and Homoallylic Alcohols with High Optical Purity
Pineschi, Mauro,Del Moro, Federica,Crotti, Paolo,Di Bussolo, Valeria,Macchia, Franco
, p. 2099 - 2105 (2007/10/03)
A novel regiodivergent kinetic resolution of a series of allylic epoxides with alkylzinc reagents is described. Results demonstrate the potential of chiral copper-phosphoramidite catalysts for enantiomer differentiation of allylic epoxides, allowing a chiral catalyst-stereoregulated synthesis of cyclic allylic and homoallylic alcohols with high optical purities.
Regioselective SN2 opening of α,β-ethylenic epoxides by RLi-BF3 combination
Alexakis, Alexandre,Vrancken, Emmanuel,Mangeney, Pierre,Chemla, Fabrice
, p. 3352 - 3353 (2007/10/03)
Organolithium reagents effect a regioselective SN2 nucleophilic cleavage of α,β-ethylenic epoxides only when BF3·Et2O is added. The reaction works with a variety of RLi reagents and with cyclic as well as acyclic epoxides. The Royal Society of Chemistry 2000.
NICKEL(II)-CATALYZED ALKYLATION OF 2-METHYL-1,3-DIOXEP-4-ENE BY GRIGNARD REAGENTS: AN EFFICIENT AND SELECTIVE ROUTE TO ALLYLIC ALCOHOLS
Menicagli, Rita,Malanga, Corrado,Finato, Barbara,Lardicci, Luciano
, p. 69 - 70 (2007/10/02)
Allylic alcohols are formed, in good yields, through the regiocontrolled Cl2Nidppe-catalyzed alkylation of 2-methyl-1,3-dioxep-4-ene by Grignard reagents .Highly pure Z alcohols arise when secondary and tertiary aliphatic Grignards are used.
