53049-06-2

Basic information

• Product Name: CYCLO(-MET-PRO)
• Synonyms: CYCLO(-MET-PRO)
• CAS NO: 53049-06-2
• Molecular Formula: C10H16N2O2S
• Molecular Weight: 228.31
• Mol File: 53049-06-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: CYCLO(-MET-PRO)(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLO(-MET-PRO)(53049-06-2)
• EPA Substance Registry System: CYCLO(-MET-PRO)(53049-06-2)

Safety Data

• Hazardous Substances Data: 53049-06-2(Hazardous Substances Data)

Usage

General Description

CYCLO(-MET-PRO) is a cyclic tripeptide composed of three amino acids: cysteine (Cys), methionine (Met), and proline (Pro). It has been found to exhibit antioxidant, anti-inflammatory, and anti-proliferative properties. CYCLO(-MET-PRO) has shown potential in reducing oxidative stress and inhibiting the production of inflammatory mediators, making it a promising candidate for the treatment of various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Research suggests that CYCLO(-MET-PRO) may function as a scavenger of reactive oxygen species and a modulator of cellular signaling pathways, contributing to its therapeutic potential. Further studies are needed to fully understand the mechanisms of action and potential applications of CYCLO(-MET-PRO) in the field of medicine and healthcare.

Upstream product

• 52899-08-8 prolyl-methionine 
• 287731-57-1 (S)-1-((S)-2-Formylamino-4-methylsulfanyl-butyryl)-pyrrolidine-2-carboxylic acid (2R,3S,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 71855-77-1 (S)-2-((S)-1-Methoxycarbonyl-3-methylsulfanyl-propylcarbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 287731-58-2 (R)-1-((S)-2-Formylamino-4-methylsulfanyl-butyryl)-pyrrolidine-2-carboxylic acid (2R,3S,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 

Relevant articles and documents

AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT

Disclosed herein is an agricultural agent containing a 2,5-diketopiperazine derivative capable of controlling plant diseases and promoting plant growth or an agriculturally acceptable salt thereof as an active ingredient.

Chemical Characterization of Diketopiperazines in Beer

Diketopiperazines (DKPs) corresponding to cyclic dipeptides have been detected in a variety of natural products as well as in processed foods, beverages, and food and beverage ingredients. A series of seven proline-based diketopiperazines, namely, cyclo(Ala-Pro), cyclo(Val-Pro), cyclo(Ile-Pro), cyclo(Leu-Pro), cyclo(Met-Pro), cyclo(Phe-Pro), and cyclo(Pro-Pro), has now been identified in beer. A marketplace cross-section of five commercial beers was studied, involving products manufactured in different countries using distinctly different raw materials and brewing styles; maximum concentrations of individual diketopiperazines in various beers ranged from below detection limit to approximately 24 ppm. The flavor characteristics of these compounds were described variously as bitter, mouth coating, drying, astringent, salty, metallic, and grainy when evaluated in water at concentrations ranging from 10 to 50 ppm. However, it is questionable whether or not the diketopiperazines reported here make a significant contribution to either the aroma or taste of most beers.