53054-77-6

Basic information

• Product Name: 2-(prop-2-en-1-yl)isoquinolinium bromide
• Synonyms: 2-Allylisoquinolinium bromide; isoquinolinium, 2-(2-propen-1-yl)-, bromide (1:1)
• CAS NO: 53054-77-6
• Molecular Formula: Br*C₁₂H₁₂N
• Molecular Weight: 250.1344
• Mol File: 53054-77-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(prop-2-en-1-yl)isoquinolinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(prop-2-en-1-yl)isoquinolinium bromide(53054-77-6)
• EPA Substance Registry System: 2-(prop-2-en-1-yl)isoquinolinium bromide(53054-77-6)

Safety Data

• Hazardous Substances Data: 53054-77-6(Hazardous Substances Data)

Upstream product

• 119-65-3 isoquinoline 
• 106-95-6 allyl bromide 

Downstream Products

• 7697-69-0 2-allylisoquinolin-1(2H)-one 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 86368-07-2 3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-ol 

Relevant articles and documents

Carbene-catalyzed aerobic oxidation of isoquinolinium salts: Efficient synthesis of isoquinolinones

A mild and environmentally friendly carbene-catalyzed aerobic oxidation of isoquinolinium salts was successfully realized. Accordingly, a diverse set of isoquinolinones and phenanthridinones was efficiently prepared in good to excellent yields. The mechanistic study indicates that the formation of an aza-Breslow intermediate is the crucial step in this transformation. This reaction features ambient air as the sole oxidant and oxygen source, a broad substrate scope, and excellent functional-group tolerance and proceeds under mild reaction conditions. Furthermore, a highly efficient synthesis of bioactive molecules and natural products including N-methylcrinasiadine, N-isopentylcrinasiadine, N-phenethylcrinasiadine, isoindolo[2,1-b]isoquinolin-5(7H)-one, PJ-34, rac-Gusanlung D, rosettacin, 8-oxopseudopalmatine and ilicifoline B was accomplished.