53055-04-2

Basic information

• Product Name: (2-Nitro-3-Methoxy-phenyl)-Methanol
• Synonyms: (2-Nitro-3-Methoxy-phenyl)-Methanol;(3-Methoxy-2-nitrophenyl)Methanol;3-methoxy-2-nitrobenzenemethanol
• CAS NO: 53055-04-2
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.16136
• Mol File: 53055-04-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 70 °C
• Boiling Point: 341.2±27.0 °C(Predicted)
• Appearance: /
• Density: 1.316±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.84±0.10(Predicted)
• CAS DataBase Reference: (2-Nitro-3-Methoxy-phenyl)-Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Nitro-3-Methoxy-phenyl)-Methanol(53055-04-2)
• EPA Substance Registry System: (2-Nitro-3-Methoxy-phenyl)-Methanol(53055-04-2)

Safety Data

• Hazardous Substances Data: 53055-04-2(Hazardous Substances Data)

Usage

General Description

(2-Nitro-3-methoxy-phenyl)-methanol, also known as NM-methanol, is a chemical compound with a nitro and methoxy functional group attached to a benzene ring. It is used in organic synthesis and pharmaceutical research as a starting material for the synthesis of various biologically active compounds. NM-methanol exhibits anti-inflammatory and analgesic properties, making it a potential candidate for the development of new drugs. Additionally, it has been studied for its potential use as a corrosion inhibitor in metal-based systems. Its molecular structure and properties make it an important compound in the field of medicinal chemistry and materials science.

Upstream product

• 5307-17-5 methyl 3-methoxy-2-nitrobenzoate 
• 5368-81-0 methyl 3-methoxybenzoate 
• 19438-10-9 methyl 3-hydroxybenzoate 
• 99-06-9 3-Carboxyphenol 
• 4920-80-3 3-methoxy-2-nitrobenzoic acid 
• 53055-05-3 3-methoxy 2-nitrobenzaldehyde 

Downstream Products

• 34112-74-8 2-Nitro-3-hydroxy-benzylalkohol 
• 18274-82-3 2-amino-3-hydroxymethyl-phenol 
• 1630732-32-9 C₃₄H₃₂N₂O₇S 
• 53055-05-3 3-methoxy 2-nitrobenzaldehyde 
• 1422192-63-9 1-Boc-3-(3-methoxy-2-nitrobenzylidene)piperidine 
• 1422192-75-3 1-Boc-3-(3-methoxy-2-nitrobenzylidene)piperidine 
• 503856-41-5 diethyl 2-nitro-3-methoxybenzylphosphonate 
• 112072-68-1 ethyl-(3-methoxy-2-nitro-benzyl)-amine 
• 102880-27-3 ethyl-(2-amino-3-methoxy-benzyl)-amine 

Relevant articles and documents

TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS IRAK4 INHIBITORS

Disclosed are compounds of Formula (I) or a salt or prodrug thereof, wherein: X11 and X22 are independently C or N, provided that zero or one of X11 and X22 is N; Ring A represented by the structure is: or; and Q, R11, R22, R33, R44, R66, and p are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

CLASS OF NEAR INFRARED MOLECULAR PROBES FOR BIOLOGICAL APPLICATIONS

Methods for preparing 2,5-Bis(benzoxazol-2′-yl)benzene-1,4-diol derivatives (Zinhbo derivatives) are provided. Zinhbo derivatives are used to detect zinc ions and have particular application in vivo and in vitro. Zinhbo derivatives upon excitation give a florescence response emission that can be used to determine the presence of zinc cation in solution. Zinhbo derivatives complexed with zinc cations upon excitation can produce a florescence response emission in the visible and near infrared range. Zinhbo derivatives complexed with zinc cations exhibit a large stoke shift between the excitation and emission wavelengths.