5309-40-0Relevant academic research and scientific papers
Oxygenated diterpenes and other constituents from Moroccan Juniperus phoenicea and Juniperus thurifera var. africana
Barrero, Alejandro F.,Quílez Del Moral, José F.,Herrador, M. Mar,Akssira, Mohamed,Bennamara, Ahmed,Akkad, Said,Aitigri, Mohamed
, p. 2507 - 2515 (2004)
Six new diterpenic acids isolated as their methyl ester together the isovalerate derivatives of p-methoxycinnamyl alcohol and 8-hydroxy-linalool, were isolated from the leaves of Juniperus thurifera and Juniperus phoenicea, grown in Morocco. The cytotoxicity of the abietane diterpenoids was tested against five cell lines. Six new diterpenic acids isolated as their methyl ester derivatives, i.e., methyl 12-oxo-8α,15-dihydroxyabiet-13-en-19-oate, methyl 12-oxo-8α-hydroxyabiet-13-en-19-oate, methyl 15-hydroperoxy- 8α,12α-epidioxiabiet-13-en-19-oate, methyl 15-hydroxy-8α, 12α-epidioxiabiet-13-en-19-oate, methyl 15-hydroperoxy-8α,14α, 12α,13α-diepoxiabietan-13-en-19-oate, and methyl 7α,12α-dihydroxysandaracopimarate, together with two new isovalerate derivatives of p-methoxycinnamyl alcohol and linalool, were isolated from the leaves of Juniperus thurifera var. africana and Juniperus phoenicea, grown in Morocco. The structures of these compounds were established by using spectroscopic techniques, including 2D NMR spectra. The cytotoxicity of the abietane diterpenoids was tested against five cell lines.
