53106-45-9

Basic information

• Product Name: [E,(-)]-3-(4-Hydroxyphenyl)propenoic acid 1-(2,3-dihydro-7-oxo-7H-furo[3,2-g][1]benzopyran-2-yl)-1-methylethyl ester
• Synonyms: (-)-Secorin;[E,(-)]-3-(4-Hydroxyphenyl)propenoic acid 1-(2,3-dihydro-7-oxo-7H-furo[3,2-g][1]benzopyran-2-yl)-1-methylethyl ester;Secorin
• CAS NO: 53106-45-9
• Molecular Formula: C23H20 O6
• Molecular Weight: 392.4
• Mol File: 53106-45-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [E,(-)]-3-(4-Hydroxyphenyl)propenoic acid 1-(2,3-dihydro-7-oxo-7H-furo[3,2-g][1]benzopyran-2-yl)-1-methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [E,(-)]-3-(4-Hydroxyphenyl)propenoic acid 1-(2,3-dihydro-7-oxo-7H-furo[3,2-g][1]benzopyran-2-yl)-1-methylethyl ester(53106-45-9)
• EPA Substance Registry System: [E,(-)]-3-(4-Hydroxyphenyl)propenoic acid 1-(2,3-dihydro-7-oxo-7H-furo[3,2-g][1]benzopyran-2-yl)-1-methylethyl ester(53106-45-9)

Safety Data

• Hazardous Substances Data: 53106-45-9(Hazardous Substances Data)

Upstream product

• 21422-04-8 7-demethylsuberosin 
• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 27421-19-8 7-(2-methylbut-3-en-2-yloxy)-2H-chromen-2-one 
• 495-32-9 marmesin 
• 27421-18-7 7-((2-methylbut-3-yn-2-yl)oxy)-2H-chromen-2-one 
• 141222-28-8 (E)-3-(4'-((tert-butyldimethylsilyl)oxy)phenyl)acrylic acid 
• 93-35-6 7-hydroxy-2H-chromen-2-one 

Relevant articles and documents

Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells

Coumarins are ubiquitous in higher plants and exhibit various biological actions. The aim of this study was to investigate the structure-activity relationships of coumarin derivatives on tert-butyl hydroperoxide (t-BHP)-induced oxidative damage in human hepatoma HepG2 cells. A series of coumarin derivatives were prepared and assessed for their cytoprotective effects. Among these, a caffeoyl acid-conjugated dihydropyranocoumarin derivative, caffeoyllomatin, efficiently protected against cell damage elicited by t-BHP. Our findings suggest that caffeoyllomatin appears to be a potent cytoprotective agent.