53118-63-1Relevant academic research and scientific papers
Lanthanoid Triflate Catalyzed Conjugate Addition of Amines to α,β-Unsaturated Esters. A Facile Route to Optically Active β-Lactam
Matsubara, Seijiro,Yoshioka, Masahito,Utimoto, Kiitiro
, p. 827 - 830 (1994)
Catalytic amount of lanthanoid(III) triflates promoted the conjugate addition of amines to 2-alkenoic acid esters to give β-amino esters.The reaction of benzylamine with α,β-unsaturated esters containing a stereogenic center at γ-position proceeded diastereoselectivity to yield optically active β-lactam precursors.
