5312-86-7Relevant academic research and scientific papers
Nitro Olefins and Organoaluminum Compounds: A Powerful Synthetic Tool in Organic Chemistry
Pecunioso, Angelo,Menicagli, Rita
, p. 2391 - 2396 (2007/10/02)
M species react with α-nitro olefins showing an unusual aptitude for a preferential transfer of saturated alkyl groups; M (R' = phenyl, benzyl, allyl) species, on the other hand, are able to transfer unsaturated groups with high chemosele
Silyl Nitronates in Organic Synthesis. Routes to Heterocycles and Cyclopentanoids. Synthesis of Allethrolone and Calythrone. Acylation and Cyanohydroxylation of Double Bonds. An Exploratory Study
Andersen, Soeren H.,Das, Nalin B.,Joergensen, Ruth D.,Kjeldsen, Gunhild,Knudsen, Jes S.,et al.
, p. 1 - 14 (2007/10/02)
Silyl nitronates are versatile reagents for the preparation of heterocycles by dipolar addition to double bonds.The intermediate isoxazolidines can be transformed to 2-isoxazolines, isoxazoles, furans, dihydrofuranones, pyrazoles, pyridazines and pyridazones.Reduction of 2-isoxazolines with Ti3+ leads to hydroxylated 1,4-diketones, which subsequently can be cyclized to cyclopentenones.Routes to calythrone, rethrolones, prostanoids and a number of naturally occurring dihydrofuranones are devised, as well as synthetic procedures for acylation, preparation of endiones, hydroxyacylation, cyanation and hydroxycyanation of double bonds.
