53120-13-1Relevant academic research and scientific papers
Gold(I)-catalyzed reactions of propargyl esters with vinyl derivatives
Sperger, Christian A.,Tungen, Jorn E.,Fiksdahl, Anne
supporting information; experimental part, p. 3719 - 3722 (2011/09/12)
A gold-catalyzed olefin cyclopropanation reaction of propargyl esters with vinyl ester or vinyl sulfonamide derivatives was investigated for the synthesis of highly substituted cyclopropane derivatives in good diastereoselectivity. By varying the vinyl sp
Synthesis of pyrimidine-containing nucleoside β-(R/S)- hydroxyphosphonate analogues
Meurillon, Maia,Chaloin, Laurent,Perigaud, Christian,Peyrottes, Suzanne
supporting information; experimental part, p. 3794 - 3802 (2011/09/30)
A concise route to nucleoside β-hydroxyphosphonate analogues is described. The use of a nucleoside β-ketophosphonate as the key intermediate allowed both the (R) and (S) isomers of β-hydroxyphosphonate analogues in the pyrimidine series to be accessed. Such derivatives may be considered as stable mimics of 5′-monophosphate nucleosides and, therefore, could be the starting point for the development of potential therapeutic agents. Copyright
Formation of enamides via palladium(II)-catalyzed vinyl transfer from vinyl ethers to nitrogen nucleophiles
Brice, Jodie L.,Meerdink, James E.,Stahl, Shannon S.
, p. 1845 - 1848 (2007/10/03)
Matrix presented. Palladium(II) complexes catalyze the formation of enamides via the formal cross-coupling reaction between nitrogen nucleophiles and vinyl ethers. These vinyl transfer reactions proceed in good yields with amide, carbamate, and sulfonamide nucleophiles, and the optimal catalyst is (DPP)Pd(OCOCF3)2 (DPP = 4,7-diphenyl-1,10-phenanthroline).
