531500-51-3 Usage
Uses
Used in Pharmaceutical Industry:
(6R,12bR)-6-(1,3-Benzodioxol-5-yl)-2,3,7,12b-tetrahydro-2-Methyl-pyrazino[1',2':1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H)-trione is used as a potential therapeutic agent for the treatment of various conditions, particularly those related to erectile dysfunction and pulmonary arterial hypertension. As a PDE5 inhibitor, it works by increasing the levels of cyclic guanosine monophosphate (cGMP), which leads to vasodilation and improved blood flow.
Used in Research Applications:
In addition to its potential clinical uses, (6R,12bR)-6-(1,3-Benzodioxol-5-yl)-2,3,7,12b-tetrahydro-2-Methyl-pyrazino[1',2':1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H)-trione is also utilized in research settings to study the role of PDE5 in various physiological processes. Researchers use (6R,12bR)-6-(1,3-Benzodioxol-5-yl)-2,3,7,12b-tetrahydro-2-Methyl-pyrazino[1',2':1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H)-trione to investigate the mechanisms of action and potential side effects associated with PDE5 inhibition, which can contribute to the development of new drugs and therapies.
Used in Drug Development:
Check Digit Verification of cas no
The CAS Registry Mumber 531500-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,1,5,0 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 531500-51:
(8*5)+(7*3)+(6*1)+(5*5)+(4*0)+(3*0)+(2*5)+(1*1)=103
103 % 10 = 3
So 531500-51-3 is a valid CAS Registry Number.
531500-51-3Relevant academic research and scientific papers
Substituted tetracyclic pyrroloquinolone derivatives useful as phosphodiesterase inhibitors
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, (2008/06/13)
The invention relates to novel tetracyclic pyrroloquinolone derivatives of the formula (I) or (II): wherein all variables are as herein defined, pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
