53165-17-6

Basic information

• Product Name: Acetamide, N-(2-formyl-4-methylphenyl)-
• CAS NO: 53165-17-6
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• Mol File: 53165-17-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(2-formyl-4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(2-formyl-4-methylphenyl)-(53165-17-6)
• EPA Substance Registry System: Acetamide, N-(2-formyl-4-methylphenyl)-(53165-17-6)

Safety Data

• Hazardous Substances Data: 53165-17-6(Hazardous Substances Data)

Upstream product

• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 1158910-14-5 N-(2-hydroxymethyl-4-methyl-phenyl)-acetamide 
• 1196-79-8 2,5-Dimethyl-1H-indole 

Downstream Products

• 4053-34-3 6-methylquinolin-2(1H)-one 
• 1003024-69-8 methyl 3-(2-acetamido-5-methylphenyl)-3-hydroxy-2-methylenepropanoate 

Relevant articles and documents

A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines

We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO2CF3 groups. The protocol is metal-, catalyst- and irradiation-free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups.

COMPOUND

There is provided a compound having Formula (I), wherein each of R1, R2, R3, R4, R5, R6, R7, R8 and R9 are independently selected from (a) H, (b) R13, -OC(R13)3, -OCH(R13)2, -OCH2R13, -C(R13)3, -CH(R13)2, or -CH2R13 wherein R13 is a halogen; (c) -CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (I) aryloxy; (m) -SO2-alkyl; and (n) -N(R14)C(O)R15, wherein R14 and R15 are independently selected from H and hydrocarbyl, wherein the optional substituents of (d) (e) (T) (h) and (i) are selected from the group consisting of: C1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, C1-6 alkoxy, carboxy, carboxyalkyl, carboxamide, mercapto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl; wherein n and p are independently selected from 0 and 1; X is an optional group selected from O, S, S=O, S(=O)2, C=O, S(=O)2NR16, C=ONR17, NR18, in which R16, R17, and R18 are independently selected from H and hydrocarbyl, R10 is selected from H and hydrocarbyl, R11 is selected from CR19R20 and C=O, in which R19 and R20 are independently selected from H and hydrocarbyl, R12 is selected from a substituted five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring, and wherein the one or more substituents are selected from hydrocarbyl groups.