53170-19-7

Basic information

• Product Name: DIMETHYL-D 6-AMINE HYDROCHLORIDE
• Synonyms: Methan-d3-amine,N-(methyl-d3)-,hydrochloride;DIMETHYL-D6 AMINE HCL;DIMETHYL-D 6-AMINE HYDROCHLORIDE;DIMETHYLAMMONIUM CHLORIDE-D6;DIMETHYLAMINE HYDROCHLORIDE-D6;DIMETHYLAMINE HCL (D6);di[(2H3)methyl]ammonium chloride;DIMETHYL-D6-AMINE HYDROCHLORIDE, 99 ATOM % D
• CAS NO: 53170-19-7
• Molecular Formula: C₂H₈N*Cl
• Molecular Weight: 87.58
• EINECS: 258-409-7
• Product Categories: Alphabetical Listings;D;Stable Isotopes
• Mol File: 53170-19-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 170-173 °C(lit.)
• Boiling Point: 47 °C at 760 mmHg
• Appearance: /
• Vapor Pressure: 322mmHg at 25°C
• Sensitive: Hygroscopic
• CAS DataBase Reference: DIMETHYL-D 6-AMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL-D 6-AMINE HYDROCHLORIDE(53170-19-7)
• EPA Substance Registry System: DIMETHYL-D 6-AMINE HYDROCHLORIDE(53170-19-7)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 53170-19-7(Hazardous Substances Data)

Usage

Chemical Properties

Solid

InChI:InChI=1/C2H7N.ClH/c1-3-2;/h3H,1-2H3;1H/i1D3,2D3;

Upstream product

• 97941-90-7 N,N-Bis-(D₃-methyl)-p-toluolsulfonamid 
• 17829-05-9 N-nitrosodimethylamine-d₆ 

Downstream Products

• 477909-75-4 1-(4-chloro-2-iodophenyl)-3,3-dimethyl-d6-triazene 
• 51219-90-0 hexamethylphosphoric triamide-D₁₈ 
• 3408-97-7 N'-(4-bromophenyl)-N,N-dimethylurea 

Relevant articles and documents

Deuterated substituted butenamide and preparation method and application thereof

The invention belongs to the field of medicines, and particularly relates to deuterated substituted butenamide and a preparation method and application thereof. The deuterated substituted butenamide is prepared from the intermediate compound shown V. Compared with the prior art, the deuterated substituted butenamide is used. The deuterated substituted butane acetamide - N - oxide has a good anti-cancer effect, and the application prospect of the medicine is increased for anti-cancer treatment drugs. , The deuterated substituted butanamide and the deuterated substituted butane acetamide - N - oxide are prepared by the process, the operation is simple, the purity is high, the three wastes are few, and the process is environment-friendly and friendly.

A practical synthesis of deuterated methylamine and dimethylamine

In recent years, several deuterated drugs have entered clinical trials and have been approved for use. Deuterated methylamine and dimethylamine as important intermediates play significant roles in the preparation of deuterated drugs. In this study, we have developed a new method to prepare deuterated methylamine and dimethylamine. This method employs Boc-benzylamine as the starting material and TsOCD3 as the deuterated methylation reagent. Our method gives relatively high yields and involves simple purifications, which provide a favourable supplement for the development and synthesis of deuterated drugs in the future.

Method for synthesizing deuterated dimethylamine salt by using halogenated deuterated methane (by machine translation)

The invention discloses a method for synthesizing deuterated dimethylamine salt with halogenated deuterated methane, which comprises the following steps: (1) reacting compound 1 with R-NH under the presence of a strong base and an inert solvent. 2 Reaction, i.e. compound 2; (2) The compound 2 is reacted with an acid to obtain a deuterated dimethylamine salt. The preparation method is simple, efficient, low in cost and good in industrial application prospect. (by machine translation)