53176-69-5Relevant academic research and scientific papers
Asymmetric microbiological Baeyer-Villiger reaction of a bridged bicyclic ketone: Divergent behaviour of its enantiomers
Konigsberger,Alphand,Furstoss,Griengl
, p. 499 - 500 (2007/10/02)
The bioconversion of 7-anti-benzyloxymethylbicyclo[2.2.1]hept-5-en-2-one 1 with cells of Acinetobacter calcoaceticus NCIB 9871 has been studied. Its (1R,4S,7R) enantiomer underwent a Baeyer-Villiger oxidation yielding rearranged lactone 2 (ee 85%), whereas (1S,4R,7S)-1 was reduced to alcohols 3-endo (ee 95%) and 3-exo (o.p. 89%).
