5318-76-3 Usage
Uses
Used in Pharmaceutical Industry:
1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride is used as a pharmaceutical compound for its potential therapeutic effects. 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride's unique structure allows it to interact with specific biological targets, making it a candidate for the development of new drugs to treat various diseases.
Used in Antiprotozoal Applications:
In the field of antiprotozoal treatment, 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride is used as an active agent against protozoan parasites, such as Babesia. Its effectiveness in targeting and eliminating these parasites makes it a valuable tool in the treatment of related infections.
Used in Veterinary Medicine:
1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride is used as a veterinary drug for the treatment of anaplasmosis, a disease caused by the Anaplasma parasite. Imidocarb dihydrochloride, a related compound, has been reported to be highly effective against this condition, with a single dosage being curative if administered early in the infection. Multiple doses may be required for later-stage treatments or in cases of relapse.
Check Digit Verification of cas no
The CAS Registry Mumber 5318-76-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,1 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5318-76:
(6*5)+(5*3)+(4*1)+(3*8)+(2*7)+(1*6)=93
93 % 10 = 3
So 5318-76-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H20N6O.2ClH/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18;;/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26);2*1H
5318-76-3Relevant academic research and scientific papers
Preparation method of 2-(3-amino phenyl) imidazoline hydrochloride and imidocarb
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, (2017/08/31)
The invention relates to the field of chemical engineering and discloses a preparation method of 2-(3-amino phenyl) imidazoline hydrochloride and imidocarb. The preparation method comprises the following steps of: inputting 2-(3-nitryl phenyl) imidazoline, a catalyst and an alcohol-water mixed solution into a reaction kettle, stirring the mixture and raising the temperature to 50-65 DEG C, keeping the temperature and stirring the mixture for 10-20 min to obtain a mixed solution M; dropwise adding formic acid into the solution M, and keeping the temperature to react for 1.5-2.5h to obtain a mixed solution N; cooling the solution N to 40 DEG C below and filtering the solution, and evaporating alcohol to obtain a 2-(3-amino phenyl) imidazoline aqueous solution; dropwise adding hydrochloric acid into the 2-(3-amino phenyl) imidazoline aqueous solution to be neutral; and performing crystallization, suction filtration, pressure reduction and drying to obtain a target product 2-(3-amino phenyl) imidazoline hydrochloride. Compared with catalytic hydrogenation in the prior art, by taking formic acid as a hydrogen donor for transfer hydrogenation, the product purity and yield are of no obvious differences but no safety risks are available, and the preparation method is free of special demand, easy to operate and convenient for production and application.
