5321-46-0

Usage

Uses

Used in Pharmaceutical Industry:
(4-CHLORODIPHENYL)METHYL BETA-CHLOROETHYL ETHER is used as an intermediate for the synthesis of various pharmaceuticals. Its role in this application is due to its chemical structure, which can be further modified to produce different medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical industry, (4-CHLORODIPHENYL)METHYL BETA-CHLOROETHYL ETHER is used as an intermediate in the production of various agrochemicals. Its chemical properties make it a suitable candidate for creating compounds that can be used in the agricultural sector.
Used in Dye Manufacturing:
(4-CHLORODIPHENYL)METHYL BETA-CHLOROETHYL ETHER is also used in the manufacturing of dyes. Its chemical composition allows for the creation of a range of dye products, contributing to its utility in this industry.
Used in Organic Compound Synthesis:
This chemical compound is utilized in the synthesis of other organic compounds due to its reactive functional groups and versatile chemical structure. Its use in this application is driven by the need for diverse building blocks in organic chemistry.

Upstream product

• 162191-86-8 C₁₃H₁₀ClO^(1-)*Na⁽¹⁺⁾ 
• 107-06-2 1,2-dichloro-ethane 
• 119-56-2 (4-chlorophenyl)phenylmethanol 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 138522-69-7 1-<2-(4-chlorophenyl)phenylmethoxyethyl>-4-piperidinecarbaldehyde 
• 109808-61-9 1-{2-[α-(4-chlorophenyl)benzyloxy]ethyl}piperazine 
• 220329-19-1 levocloperastine fendizoate 
• 3703-76-2 Cloperastine 
• 175692-17-8 {2-[(4-Chloro-phenyl)-phenyl-methoxy]-ethyl}-methyl-amine 
• 5617-26-5 β-Morpholinoethyl-4-chlorbenzhydrylether 
• 116152-62-6 1-(4-tert-butyl-benzyl)-4-[2-(4-chloro-benzhydryloxy)-ethyl]-piperazine 

Relevant academic research and scientific papers

A left hand chlorine paipai Si Tingfenoak acid preparation method of the

The invention discloses a preparation method of levo cloperastine fendizoate, which comprises the following steps: carrying out nucleophilic substitution reaction on 4-chlorobenzhydrol and 2-chloroethanol in a benzene organic solvent, so that an intermediate product is obtained; reacting the intermediate product with piperidine, so that racemic cloperastine is obtained; resolving the racemic cloperastine by using a resolving agent in a fatty alcohol solvent, so that levo cloperastine is obtained; and carrying out salt forming reaction on the levo cloperastine and a fendizoic acid, so that levo cloperastine fendizoate is obtained, wherein the resolving agent is an R-substituted dibenzoyl-L-tartaric acid, and R refers to alkyl, alkoxy, -Cl, -F, -Br or -H. In the method provided by the invention, in a fatty alcohol solvent, an R-substituted dibenzoyl-L-tartaric acid is adopted as a resolving agent for carrying out resolving on racemic cloperastine, and the resolving yield is high, so that the obtained levo cloperastine fendizoate has high optical purity, and has a high product yield.

Synthesis of azolylethyl benzhydryl ethers, analogs of diphenhydramine

Alternative approaches to the preparation of azolylethyl benzhydryl ethers have been studied. It was shown that the reaction of diphenylmethyl halide with 2-(azol-1-yl)ethanol in the presence of triethylamine is the optimum way. An efficient method for the synthesis of 2-(imidazol-1-yl)ethanol using phase-transfer catalysis has been developed.

Synthesis and psychoanaleptic properties of new compounds structurally related to diphenhydramine

A new series of benzhydryloxyalkylpiperazines carrying a trivalent function has been synthesized and studied for its effects on the central nervous system. Most of the compounds exhibit unexpected nonamphetaminic psychoanaleptic properties. The structure-