53234-66-5Relevant academic research and scientific papers
A new source of methylene Meldrum's acid. Reactions with enamines
Smith, Francis X.,Williams, Brian D.,Evans, Edward C.
, p. 2009 - 2015 (2007/10/03)
The unsymmetrical Knoevenagel-Michael product derived from Meldrum's acid, phenyl Meldrum's acid and formaldehyde was prepared as a pure, stable and crystalline product. This compound readily dissociates under the reaction conditions to produce methylene
Synthesis of 3-azabicyclo[3.3.1]Nonane-6,9-diones
Williams, Brian D.,Williams, Birute,Bernardoni, Francis,Finn, Robert C.,Zubieta, Jon
, p. 2199 - 2206 (2007/10/03)
A one pot synthesis of 3-azabicyclo[3.3.1]nonane-6,9-diones is described via the additibn of acryloyl chloride to enamines of N-carboxy-4 piperidones. Yields of bicycle were highest when additions were made to vigorously boiling solutions of morpholine en
FUNCTIONALIZED CHLOROENAMINES IN AMINOCYCLOPROPANE SYNTHESIS - VI. CHLOROTETRAHYDROPYRIDINES AS A BASIS FOR THE SYNTHESIS OF 3-AZABICYCLOHEXANE DERIVATIVES
Tetzlaff, Claus,Vilsmaier, Elmar,Schlag, Wolf-Ruediger
, p. 8117 - 8130 (2007/10/02)
Enamine 8a-e could be chlorinated by equimolar amounts of N-chlorosuccinimide (9) generating monochloroenamines 10a-e; 10a and 10d were isolated as pure substances.Two equivalents of 9 afforded the dichloroenamines 12a,c from 8a,c.Interaction of the chlor
