53244-19-2

Basic information

• Product Name: 2-methyl-5-phenylpentanenitrile
• Synonyms: 2-methyl-5-phenylpentanenitrile
• CAS NO: 53244-19-2
• Molecular Weight: 173.258
• Mol File: 53244-19-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-methyl-5-phenylpentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-5-phenylpentanenitrile(53244-19-2)
• EPA Substance Registry System: 2-methyl-5-phenylpentanenitrile(53244-19-2)

Safety Data

• Hazardous Substances Data: 53244-19-2(Hazardous Substances Data)

Upstream product

• 108139-26-0 (3-phenylpropylidene)propanedinitrile 
• 151-50-8 potassium cyanide 
• 637-59-2 1-Bromo-3-phenylpropane 
• 107-12-0 propiononitrile 
• 13633-25-5 1-Bromo-4-phenylbutane 

Downstream Products

• 36613-11-3 rac-2-Methyl-5-phenylpentanal 
• 2235-83-8 5-phenyl-2-pentanone 
• 143097-60-3 (±)-2-methyl-5-phenylpentanoic acid 

Relevant articles and documents

Non-reductive decyanation reactions of disubstituted malononitrile derivatives promoted by NaHMDS

A new method for achieving the decyanation of disubstituted malononitrile derivatives without using reducing agents has been developed. Treatment of a six-membered malononitrile derivative with NaHMDS followed by methanol afforded the corresponding acetonitrile derivative in high yield. The present method was applicable to the decyanation reactions of a variety of malononitriles including four- and five-membered compounds as well as acyclic ones.

Anodic benzylic C(sp3)-H amination: Unified access to pyrrolidines and piperidines

An electrochemical aliphatic C-H amination strategy was developed to access the important heterocyclic motifs of pyrrolidines and piperidines within a uniform reaction protocol. The mechanism of this unprecedented C-H amination strategy involves anodic C-H activation to generate a benzylic cation, which is efficiently trapped by a nitrogen nucleophile. The applicability of the process is demonstrated for 40 examples comprising both 5- and 6-membered ring formations.