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2-quinolin-8-yloxyacetic acid, also known as quinolin-8-yloxyacetic acid, is an organic compound characterized by its molecular formula C12H9NO3. It presents as a yellow crystalline powder, which is insoluble in water but readily soluble in organic solvents. This versatile chemical serves as a fundamental building block in the synthesis of pharmaceuticals and pesticides, and its potential applications extend to the treatment of various diseases, including cancer. Its anti-inflammatory and antioxidant properties have garnered interest in the field of medicinal chemistry, positioning it as a compound with significant therapeutic potential.

5326-89-6

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5326-89-6 Usage

Uses

Used in Pharmaceutical Synthesis:
2-quinolin-8-yloxyacetic acid is utilized as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs with diverse therapeutic applications.
Used in Pesticide Production:
In the agricultural sector, 2-quinolin-8-yloxyacetic acid is employed as a precursor in the production of pesticides, aiming to enhance crop protection and yield.
Used in Cancer Treatment Research:
2-quinolin-8-yloxyacetic acid is studied for its potential role in the treatment of cancer, as it may exhibit properties that can target and mitigate the progression of the disease.
Used in Medicinal Chemistry for Disease Treatment:
2-quinolin-8-yloxyacetic acid is explored for its potential use in treating a variety of diseases beyond cancer, due to its demonstrated anti-inflammatory and antioxidant properties, which could be beneficial in managing different pathological conditions.
Used in Antioxidant and Anti-inflammatory Therapies:
2-quinolin-8-yloxyacetic acid is considered for its application in antioxidant and anti-inflammatory therapies, where its properties could help in the treatment of conditions associated with oxidative stress and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 5326-89-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,2 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5326-89:
(6*5)+(5*3)+(4*2)+(3*6)+(2*8)+(1*9)=96
96 % 10 = 6
So 5326-89-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO3/c13-10(14)7-15-9-5-1-3-8-4-2-6-12-11(8)9/h1-6H,7H2,(H,13,14)

5326-89-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-quinolin-8-yloxyacetic acid

1.2 Other means of identification

Product number -
Other names quinoline-8-oxy-acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5326-89-6 SDS

5326-89-6Upstream product

5326-89-6Relevant academic research and scientific papers

A rhodamine-quinoline based chemodosimeter capable of recognising endogenous OCl- in human blood cells

Goswami, Shyamaprosad,Das, Sangita,Aich, Krishnendu,Nandi, Prasanta Kumar,Ghoshal, Kakali,Quah, Ching Kheng,Bhattacharyya, Maitree,Fun, Hoong-Kun,Abdel-Aziz, Hatem A.

, p. 24881 - 24886 (2014/07/07)

A rhodamine-quinoline based chemodosimeter (RHQ) has been designed, synthesized and characterized in this paper. The structure of the sensor is confirmed through single crystal X-ray study. It detects hypochlorite (OCl -) selectively among other analytes studied. It showed colorimetric and orange-red fluorescence "turn-on" upon addition of OCl -. The OCl--promoted ring opening of the rhodamine spirolactam ring in RHQ evokes a large absorbance as well as fluorescence enhancement in water-acetonitrile (1/1, v/v) medium with no significant response to other competitive analytes. Furthermore, we demonstrate here that RHQ can endogenously detect OCl- in human blood cells (peripheral blood mononuclear cells). It also exhibits excellent performance in the "dip stick" method. The optimized structure of the probe is calculated by density functional theory calculations. Moreover, the limit of detection of the probe is in the 10-8 M range.

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