53269-37-7 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-pyridyl)-3-(2-pyridylamino)-2-pyridone is used as a building block for the synthesis of various organic compounds and drugs. Its unique structure and properties make it a promising candidate for the development of new therapies and materials.
Used in Biochemical Research:
In the field of biochemical research, 1-(2-pyridyl)-3-(2-pyridylamino)-2-pyridone is used for its potential biological activity, which can contribute to the advancement of scientific understanding and the creation of novel treatments and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 53269-37-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,2,6 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 53269-37:
(7*5)+(6*3)+(5*2)+(4*6)+(3*9)+(2*3)+(1*7)=127
127 % 10 = 7
So 53269-37-7 is a valid CAS Registry Number.
53269-37-7Relevant academic research and scientific papers
Cine substitution in reaction of unactivated 2-halopyridines with 2-aminopyridine 1-oxide. Formation of 3-(2-pyridylamino)-2(1H)-pyridone [1]
Rykowski,Pucko
, p. 2378 - 2383 (2007/10/03)
Reaction of 2-aminopyridine 1-oxide 1a with2-fluoropyridine 5a in DMF at 140°C gave 2-(2-pyridylamino)pyridine 1-oxide 6 (41%) along with bis(2-pyridyl)amine 7 (5%). However, heating in melt of 1a with 2-chloropyridine 5b or 2-bromopyridine 5c in the presence of dry potassium carbonate at 175°C provided 3-(2-pyridylamino)-2(1H)-pyridone 9 as cine substitution product. Compound 9 results from the nucleophilic attack of the N-oxide on the carbon atom bearing halogen to give corresponding cation 17, which rearranges to cine substitution product 9 via anhydro-base 18.
