53282-36-3

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 51425-65-1 Trimethyl-((Z)-2-phenyl-propenyloxy)-silane 
• 51425-64-0 2-Phenylpropionalehyd-enol-trimethylsilylether 
• 51075-23-1 trimethyl((2-phenylprop-1-en-1-yl)oxy)silane 

Downstream Products

• 128925-85-9 ((Z)-2-phenyl-1-propen-1-yl)triphenylphosphonium triflate 
• 128925-83-7 ((E)-2-phenyl-1-propen-1-yl)triphenylphosphonium triflate 
• 105376-43-0 2-(2-phenylprop-1-en-1-yl)aniline 
• 1373751-97-3 C₁₅H₁₅N₃ 
• 1373752-17-0 C₁₅H₁₇N 

Relevant academic research and scientific papers

Insertion of Alkylidene Carbenes into B-H Bonds

We have developed a protocol for insertion of alkylidene carbenes into the B-H bonds of amine-borane adducts, enabling, for the first time, the construction of C(sp2)-B bonds by means of carbene-insertion reactions. Various acyclic and cyclic alkenyl borane-amine adducts were prepared from readily accessible starting materials in good to high yields and were subsequently subjected to a diverse array of functional group transformations. The unprecedented spiro B-N heterocycles prepared in this study have potential utility as building blocks for the synthesis of pharmaceuticals. Preliminary mechanistic studies suggest that insertion of the alkylidene carbenes into the B-H bonds of the amine-borane adducts proceeds via a concerted process involving a three-membered-ring transition state.

Rh2(II)-catalyzed intramolecular aliphatic C-H bond amination reactions using aryl azides as the N-atom source

Rhodium(II) dicarboxylate complexes were discovered to catalyze the intramolecular amination of unactivated primary, secondary, or tertiary aliphatic C-H bonds using aryl azides as the N-atom precursor. While a strong electron-withdrawing group on the nitrogen atom is typically required to achieve this reaction, we found that both electron-rich and electron-poor aryl azides are efficient sources for the metal nitrene reactive intermediate.

Intramolecular Ir(I)-catalyzed benzylic C-H bond amination of ortho-substituted aryl azides

Image Persented Iridium(I) catalyzes the intramolecular benzylic C-H bond amination of ortho-homobenzyl-substituted aryl azides to produce indolines at 25 °C.