5332-51-4Relevant articles and documents
A Chiral Stationary Phase Derived from (R,R)-Tartramide with Broadened Scope of Application to the Liquid Chromatographic Resolution of Enantiomers
Dobashi, Yasuo,Hara, Shoji
, p. 2490 - 2496 (1987)
An understanding of the retention process of solute enantiomers on a chiral stationary phase (CSP) would indicate the importance of eliminating the nonenantioselective, i.e., solute-silanol, interaction that occurs in this process.For clarification of this matter, a CSP in which a (R,R)-N,N'-dialkyltartramide derivative is linked to the silica gel surface via 11 methylene units and the remaining silanol groups are trimethylsilylated was synthesized.This CSP was found capable of chiral recognition of broad categories of enantiomers containing α- or β-hydroxycarbonyl, α-amino acid, β-aminoalcohol, primary amine derivatives, barbiturates, glutarimide, α-hydroxy ketoximes, carbinols, 1,2-diols, and bi-β-naphthol.The driving force to bring about enantioselective association is ascribable to hydrogen bonding.The effects of a reduction in the number of remaining silanol groups on CSP and a long alkyl chain as a linkage of the tetramide moiety to CSP are discussed on the basis of retentivity of enantiomers.
A Molecular Iron-Based System for Divergent Bond Activation: Controlling the Reactivity of Aldehydes
Chatterjee, Basujit,Jena, Soumyashree,Chugh, Vishal,Weyhermüller, Thomas,Werlé, Christophe
, p. 7176 - 7185 (2021/06/30)
The direct synthesis of amides and nitriles from readily available aldehyde precursors provides access to functional groups of major synthetic utility. To date, most reliable catalytic methods have typically been optimized to supply one product exclusively. Herein, we describe an approach centered on an operationally simple iron-based system that, depending on the reaction conditions, selectively addresses either the C=O or C-H bond of aldehydes. This way, two divergent reaction pathways can be opened to furnish both products in high yields and selectivities under mild reaction conditions. The catalyst system takes advantage of iron's dual reactivity capable of acting as (1) a Lewis acid and (2) a nitrene transfer platform to govern the aldehyde building block. The present transformation offers a rare control over the selectivity on the basis of the iron system's ionic nature. This approach expands the repertoire of protocols for amide and nitrile synthesis and shows that fine adjustments of the catalyst system's molecular environment can supply control over bond activation processes, thus providing easy access to various products from primary building blocks.
Maleic imide base three ethoxy silane series compound synthesis and self-assembly film preparation method
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Paragraph 0025; 0027; 0028-0030, (2019/06/26)
Among various factors influencing performances of organic electronic components, interfacial property is the most important one influencing the performance of the whole component. In the invention, a series of maleimidotriethoxy silane-series compounds are synthesized, wherein a monomolecular film layer is formed on a surface of an oxide substrate through a self-assembling method, thereby modifying the substrate. Dicyclopentadiene platinum chloride is employed as a catalyst to perform hydrosilylation. Nuclear magnetism is carried out for representation. A test result proves that the catalyst allows catalytic addition to a compound having an amino group to be carried out high-efficiently, and furthermore, silicone on a silanoethoxyl group is connected to a position of a terminal group of a double bond before addition. A self-assembling method is utilized to form the monomolecular film layer on the surface of the oxide substrate. A Young contact angle instrument and XPS is employed for representation, which proves that a flat monomolecular film layer is formed on the surface of the oxide substrate.
Base catalyzed sustainable synthesis of phenyl esters from carboxylic acids using diphenyl carbonate
Kreye, Oliver,Meier, Michael A. R.
, p. 53155 - 53160 (2015/06/25)
Phenyl esters were obtained in moderate to high yields by reaction of aliphatic and aromatic carboxylic acids with one equivalent of diphenyl carbonate in the presence of catalytic amounts of tertiary amine bases, such as DBU, TBD and DMAP under neat conditions at elevated temperatures (>100°C).
