53348-88-2

Basic information

• Product Name: 2-phenyl-benzofuran-6-carbaldehyde
• Synonyms: 2-phenyl-benzofuran-6-carbaldehyde
• CAS NO: 53348-88-2
• Molecular Weight: 222.243
• Mol File: 53348-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenyl-benzofuran-6-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-benzofuran-6-carbaldehyde(53348-88-2)
• EPA Substance Registry System: 2-phenyl-benzofuran-6-carbaldehyde(53348-88-2)

Safety Data

• Hazardous Substances Data: 53348-88-2(Hazardous Substances Data)

Upstream product

• 135242-71-6 3-hydroxy-4-iodobenzaldehyde 
• 108-86-1 bromobenzene 

Downstream Products

• 57045-53-1 2-phenyl-6-(p-cyano-styryl)benzo [b] furan 

Relevant articles and documents

Tandem Sonogashira-Hagihara coupling/cycloisomerization reactions of ethynylboronic acid MIDA ester to afford 2-heterocyclic boronic acid MIDA esters: A concise route to benzofurans, indoles, furopyridines and pyrrolopyridines

A one-pot process that provides direct access to 2-heterocyclic MIDA (N-methyliminodiacetic acid) boronates has been developed. The reaction of 2-iodophenols or 2-iodoanilines with ethynylboronic acid MIDA ester readily afforded 2-substituted heterocyclic compounds. Amidine and phosphazene bases, especially TMG (1,1,3,3-tetramethylguanidine) assumed an important role in the tandem Sonogashira-Hagihara coupling/cycloisomerization reactions.