5335-79-5Relevant academic research and scientific papers
Synthesis and Photochemistry of a New Class of Photocleavable Protein Cross-linking Reagents
Milanesi, Lilia,Reid, Gavin D.,Beddard, Godfrey S.,Hunter, Christopher A.,Waltho, Jonathan P.
, p. 1705 - 1710 (2007/10/03)
A new series of photocleavable protein cross-linking reagents based on bis(maleimide) derivatives of diaryl disulfides have been synthesised. They have been functionalised with cysteine and transient absorption spectra for the photolysis reaction have been recorded by using the pump-probe technique with a time resolution of 100 femtoseconds. Photolysis of the disulfide bond yields the corresponding thiyl radicals in less than a picosecond. There is a significant amount of geminate recombination, but some of the radicals escape the solvent cage and the quantum yield for photocleavage is 30% in water.
PHOTOCHEMICAL SUBSTITUTION OF HALOGEN AND SO2X GROUPS BY THIOUREA AND THIOSEMICARBAZIDE. PHOTOSYNTHESIS OF AROMATIC DISULFIDES
Frolov, A. N.,Klokova, E. M.,El'tsov, A. V.
, p. 1926 - 1935 (2007/10/02)
During UV irradiation in the presence of thiourea (or thiosemicarbazide) the para- and ortho-halogen and sulfonyl derivatives of the benzene, naphthalene, and heterocyclic series with donating substituents in the ring are converted into arylisothiuronium salts.Thermal hydrolysis and oxidation of these salts lead to the formation of the respective diaryl disulfides in the case of the para isomers and thiazoles for the ortho isomers.
