5335-80-8

Upstream product

• 5858-18-4 2,5-dichlorbenzenethiol 
• 51985-54-7 2,5-dichloro-benzenesulfonic acid-anhydride 
• 5402-73-3 2,5-dichlorobenzenesulphonyl chloride 
• 1762-78-3 2,5-dichlorobenzenesulfenyl chloride 
• 64-17-5 ethanol 
• 16601-12-0 S-(4-toluenesulfonyl) 4-toluenethiosulfonate 
• 861784-58-9 2-nitro-benzenethiosulfonic acid S-(2,5-dichloro-phenyl ester) 
• 95-82-9 2,5 dichloroaniline 
• 106-46-7 para-dichlorobenzene 
• 89-61-2 2,5-dichloronitrobenzene 
• 1364683-79-3 C₇H₆Cl₂O₂S 
• 3226-39-9 1,4-dichloro-2-thiocyanatobenzene 

Downstream Products

• 1762-78-3 2,5-dichlorobenzenesulfenyl chloride 
• 109041-33-0 bis-(2,5-dichloro-phenyl)-trisulfide 
• 4184-62-7 Monothiophosphorsaeure-O,O-dimethylester-S-<2,5-dichlor-phenylester> 
• 398-75-4 (2,5-dichlorophenyl) trifluoromethyl sulfide 
• 861784-58-9 2-nitro-benzenethiosulfonic acid S-(2,5-dichloro-phenyl ester) 

Relevant academic research and scientific papers

Visible-light-induced metal and reagent-free oxidative coupling of: Sp 2 C-H bonds with organo-dichalcogenides: Synthesis of 3-organochalcogenyl indoles

Here, a unique visible-light-induced method for the organochalcogenation of the sp2 C-H bonds of indoles and aniline has been presented using diaryl dichalcogenides (S, Se, and Te) and oxygen as an oxidant avoiding a photocatalyst, base, catalyst, and reagent in acetone at room temperature. This benign protocol allows one to access a wide range of 3-arylselenylindoles, 3-arylthioindoles and even 3-aryltelluroindoles with good to excellent yields. Various functionalities namely, methoxy, and halo either on indoles or aryl dichalcogenides showed amenability to the developed reaction. Furthermore, thiocyanation of the sp2 C-H bonds of indoles has been accomplished by this visible light induced method. A mechanistic understanding by UV-visible, EPR spectroscopy, and cyclic voltammetry suggests that light induces electron transfer from the electron rich arene to oxygen providing an arene radical cation and a superoxide radical anion. Subsequently, reaction of the radical cation with aryl dichalcogenides provides a diaryl chalcogenyl cation which upon removal of protons gave unsymmetrical 3-indolyl aryl chalcogenides.

An Organodiselenide with Dual Mimic Function of Sulfhydryl Oxidases and Glutathione Peroxidases: Aerial Oxidation of Organothiols to Organodisulfides

A novel organodiselenide, which mimics sulfhydryl oxidases and glutathione peroxidase (GPx) enzymes for oxidation of thiols by oxygen and hydrogen peroxide, respectively, into disulfides has been presented. The developed catalyst oxidizes an array of organothiols into respective disulfides in practical yields by using aerial O2 to avoid any reagents/additives, base, and light source. The synthesized diselenide also catalyzes the reduction of hydrogen peroxide into water by following the GPx enzymatic catalytic cycle with a reduction rate of 49.65 ± 3.7 μM·min-1.

PIPERIDINE-DIONE DERIVATIVES FOR USE AS CONTRACEPTIVES

The invention relates to a method of reducing sperm motility or of contraception in a subject, said method comprising the step of administering to said subject an effective amount of a compound of formula (I), a stereoisomer, tautomer, pharmaceutically ac

LDHA ACTIVITY INHIBITORS

The invention provides compounds of formula (I), stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof: (I) wherein A1 to A6 and R1 to R4 are as defined herein. Such compounds are suit

FLUOROALKYLATING AGENT

Problem to be Solved It is intended to provide an industrially preferable fluoroalkylating agent and use thereof. Solution The present invention provides a fluoroalkylating agent represented by the general formula (1) wherein R1 is a C1 to C8 fluoroalkyl group; R2 and R3 are each independently a C1 to C12 alkyl group or the like; Y1 to Y4 are each independently a hydrogen atom, a halogen atom, or the like; and X? is a monovalent anion. A compound of the general formula (3): R4—S—R1 having an introduced C1 to C8 fluoroalkyl group is easily obtained by reacting a compound of the general formula (2): R4—S—Z wherein R4 is a hydrocarbon group or the like; and Z is a leaving group, with the compound of the general formula (1).

Synthesis of diaryl disulfides via mild reduction of arylsulfinates with hydrazine monohydrate in DMSO

Arylsulfinates were reduced with hydrazine monohydrate at room temperature in dimethylsulfoxide (DMSO) to afford diaryl disulfides in good yields. A dramatic solvent effect was observed, and DMSO was found to be the best solvent for the reaction. Copyright Taylor & Francis Group, LLC.

Synthesis of aryl perfluoroalkyl sulfides from aromatic disulfides

Thermolysis of xenon(II) bis(perfluoroalkanecarboxylates) in the presence of diaryl disulfides occurs through the S-S bond cleavage to form dihalo-, halonitro-, and halodinitrophenyl perfluoroalkyl sulfides. The latter type of compounds was obtained for the first time. The main side process is the perfluoroalkylation of the aromatic ring.

Fusidic acid derivatives

A method for treating arthritis which comprises administering to a subject in need of such treatment an effective amount of a fusidic acid derivative selected from compounds of the formula I: STR1 in which R1 stands for a straight or branched alkyl radical having from 1 to 12 carbon atoms, and pharmaceutically acceptable, non-toxic salts and easily hydrolyzable esters thereof, and salts of such esters. The pure diastereomers as well as mixtures thereof may be used in carrying out the invention.