53359-41-4Relevant academic research and scientific papers
Synthesis of novel pyrano[2,3-b]pyridines from α,α′- bis(substituted-benzylidene)cycloalkanones
Bigdeli, Mohammad Ali,Marjani, Katayon,Farokhi, Elinaz,Sheikhhosseini, Enayatollah,Ghazanfari, Dadkhoda
, p. 625 - 629 (2013)
In this paper, we describe a two-step synthesis of a series of tacrine analogues. In the first step, α,α'-bis(substituted-benzylidene) cycloalkanones are reacted with malononitrile to afford 2-amino-3-cyano-4H- pyrans. The second step involves the convers
Clean, one-pot synthesis of 4H-pyran derivatives catalyzed by hexadecyltrimethyl ammonium bromide in aqueous media
Jin, Tong-Shou,Liu, Li-Bin,Zhao, Ying,Li, Tong-Shuang
, p. 1859 - 1863 (2007/10/03)
An efficient and convenient synthetic route to 4H-pyran derivatives in water in the presence of hexadecyltrimethyl ammonium bromide (HTMAB) as catalyst is described. This method provides several advantages such as environment friendliness, high yields, an
Synthesis of 2-aminopyran derivatives and 3-arylpropionitrile derivatives catalyzed by KF/Al2O3
Wang, Xiang-Shan,Shi, Da-Qing,Du, Ya,Zhou, Yan,Tu, Shu-Jiang
, p. 1425 - 1432 (2007/10/03)
A series of 2-cyano-3-aryl-3-(3,4-dihydro-1(2H)-naphthalene-one-2-yl) propionitrile derivatives and 2-aminopyran derivatives were synthesized by the KF-Al2O3-catalyzed reaction of malononitrile with 2-arylmethylidene-3,4-dihydro-1(2H
Studies on Cinnamonitriles: The Reaction of Cinnamonitriles with Cyclopentanone
Sofan, Mamdouh A.,El-Taweel, Fathy M.,Elagamey, Abdel Ghani A.,Elnagdi, Mohamed H.
, p. 935 - 936 (2007/10/02)
Cyclopentanone reacts with arylidenemalononitriles 1a-c to give dihydro-4,6-indenedicarbonitriles 5a-c.Similarly, the diethyl dihydro-4,6-indenedicarboxylate derivative 6 is formed when treating ethyl α-cyanocinnamate (1d) with cyclopentanone.Cyclopentab
A NOVEL SYNTHETIC ROUTE TO PHENYL-SUBSTITUTED PYRIDINES; SYNTHESIS OF BENZOPYRANOPYRIDINES, BENZOTHIOPYRANOPYRIDINES AND PYRIDOBENZOTHIAZINES(1-AZAPHENOTHIAZINES)
Tyndall, D. V.,Al Nakib, T.,Meegan, M. J.
, p. 2703 - 2706 (2007/10/02)
Reaction of 1,3-diphenylpropenone with malononitrile in base affords 1,4-diphenyl-2-methoxypyridine-3-carbonitrile.This reaction has been applied to a general synthesis of phenyl-substituted benzopyranopyridines, benzothiopyranopyridines and pyridobenzothiazines(1-azaphenothiazines).
Differences between the Reaction of 2-Benzylidenecyclopentanone with Malononitrile and the Reaction of Cyclopentylidenemalononitrile with Aromatic Aldehydes; Synthesis of Strong Fluorescent o-Aminonitriles
Mirek, Julian,Milart, Piotr
, p. 1471 - 1478 (2007/10/02)
It was found that instead of the Knoevenagel condensation of cyclopentylidenemalononitrile with aromatic aldehydes, a complex reaction takes place leading to 5,7-dicyano-1-arylidene-4-arylindanes.The same compounds were formed in the reaction of the cyclopentylidenemalononitrile dimer with aldehydes.It is suggested that the cyclopentylidenemalononitrile dimers undergo an electrocyclic ring opening leading to conjugated triene systems.These species are very reactive intermediates and may react with aldehydes in the next step.Bulky substituents in 2,5-dibenzylidenecyclopentanone hindered its Knoevenagel condensation with malononitrile but did not hinder its Michael addition leading to a 4H-pyrane derivative.Solutions of the obtained o-aminonitriles exhibit strong fluorescence in a variety of solvents. - Keywords: 2-Benzylidenecyclopentanone, Cyclopentylidenemalononitrile, o-Aminonitriles, Luminescent Spectra
