533884-41-2Relevant academic research and scientific papers
Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 2: Structure-activity relationship studies on the benzopyran scaffold
Richardson, Timothy I.,Norman, Bryan H.,Lugar, Charles W.,Jones, Scott A.,Wang, Yong,Durbin, Jim D.,Krishnan, Venkatesh,Dodge, Jeffrey A.
, p. 3570 - 3574 (2007)
Benzopyrans are selective estrogen receptor (ER) β agonists (SERBAs), which bind the ER subtypes α and β in opposite orientations. Here we describe structure-activity relationship studies that led to the discovery of bezopyran 5b. X-ray crystal structures
