533924-09-3Relevant academic research and scientific papers
Total synthesis of the antitumor acetogenin mosin B: Desymmetrization approach to the stereodivergent synthesis of threo/trans/erythro-type acetogenins
Maezaki, Naoyoshi,Kojima, Naoto,Sakamoto, Atsunobu,Tominaga, Hiroaki,Iwata, Chuzo,Tanaka, Tetsuaki,Monden, Morito,Damdinsuren, Bazarragchaa,Nakamori, Shoji
, p. 389 - 399 (2007/10/03)
A total synthesis of the threo/trans/erythro-type acetogenin mosin B and one of its diastereomers has been achieved. The carbon skeleton is assembled in a convergent fashion from two segments (a THF ring segment and a γ-lactone segment) through the Nozaki
First total synthesis of mosin B.
Maezaki,Kojima,Sakamoto,Iwata,Tanaka
, p. 429 - 432 (2007/10/03)
[figure: see text] The first total synthesis of mosin B and a diastereomer was accomplished using asymmetric desymmetrization of the sigma-symmetric diol and the Nozaki-Hiyama-Kishi reaction as the key steps. The THF core segment was stereoselectively con
