533934-52-0 Usage
Uses
Used in Organic Synthesis:
2-(p-methoxybenzyloxymethyl)phenylboronic acid serves as a reagent in Suzuki-Miyaura cross-coupling reactions, which are pivotal for the formation of carbon-carbon bonds in organic molecules. Its application in this process is crucial for the synthesis of complex organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(p-methoxybenzyloxymethyl)phenylboronic acid has demonstrated potential, particularly in the development of cancer treatments. Its unique structure and reactivity contribute to its role in the advancement of pharmaceuticals targeting various types of cancer.
Used in Drug Discovery Research:
2-(p-methoxybenzyloxymethyl)phenylboronic acid's properties also make it a valuable tool in drug discovery research, where it can be employed to explore new avenues for the creation of effective therapeutic agents, especially in oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 533934-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,3,9,3 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 533934-52:
(8*5)+(7*3)+(6*3)+(5*9)+(4*3)+(3*4)+(2*5)+(1*2)=160
160 % 10 = 0
So 533934-52-0 is a valid CAS Registry Number.
533934-52-0Relevant academic research and scientific papers
Intramolecular reactions of alkynes with furans and electron rich arenes catalyzed by PtCl2: The role of platinum carbenes as intermediates
Martin-Matute, Belen,Nevado, Cristina,Cardenas, Diego J.,Echavarren, Antonio M.
, p. 5757 - 5766 (2007/10/03)
5-(2-Furyl)-1-alkynes react, with PtCl2 as catalyst, to give phenols. On the basis of DFT calculations, a cyclopropyl platinacarbene complex was found as the key intermediate in the process. The cyclopropane and dihydrofuran rings of this intermediate open to form a carbonyl compound, which reacts with the platinum carbene to form an oxepin, which is in equilibrium with an arene oxide. When the reaction is carried out in the presence of water, dicarbonyl compounds are obtained, which support the proposed mechanism. Other cyclizations of alkynes with furans or electron-rich arenes give products of apparent Friedel-Crafts-type reactions, although these processes could also proceed by pathways involving the formation of cyclopropyl platinum carbenes.
