53396-33-1

Basic information

• Product Name: N-(N-HEXADECYL)FORMAMIDE
• Synonyms: N-(N-HEXADECYL)FORMAMIDE;N-FORMYL-N-HEXADECYLAMINE
• CAS NO: 53396-33-1
• Molecular Formula: C17H35NO
• Molecular Weight: 269.47
• Mol File: 53396-33-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 43-44 °C
• Boiling Point: 401.7°C at 760 mmHg
• Flash Point: 248.9°C
• Appearance: /
• Density: 0.854g/cm³
• Vapor Pressure: 1.16E-06mmHg at 25°C
• Refractive Index: 1.449
• PKA: 16.39±0.23(Predicted)
• CAS DataBase Reference: N-(N-HEXADECYL)FORMAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(N-HEXADECYL)FORMAMIDE(53396-33-1)
• EPA Substance Registry System: N-(N-HEXADECYL)FORMAMIDE(53396-33-1)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 53396-33-1(Hazardous Substances Data)

Usage

General Description

N-(N-hexadecyl)formamide is a chemical compound that belongs to the class of amides, which are derived from carboxylic acids. It is characterized by the presence of a hexadecyl group attached to the nitrogen atom of the formamide molecule. This chemical is commonly used in various industrial and research applications, including as a surfactant in the production of emulsions, as a solvent in organic synthesis, and as a component in various chemical reactions. N-(N-hexadecyl)formamide is also known for its ability to enhance the solubility of hydrophobic substances in aqueous solutions, making it useful in processes where such solubility is desired. However, it should be handled with care due to its potential health hazards and environmental impact.

InChI:InChI=1/C17H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-17-19/h17H,2-16H2,1H3,(H,18,19)

Upstream product

• 143-27-1 hexadecylamine 
• 68-12-2 N,N-dimethyl-formamide 
• 50-00-0 formaldehyd 
• 802294-64-0 propionic acid 
• 109-94-4 formic acid ethyl ester 
• 111333-97-2 formic acid pentafluorophenyl ester 

Relevant articles and documents

KOtBu-Promoted Transition-Metal-Free Transamidation of Primary and Tertiary Amides with Amines

This work discloses transamidation of primary and tertiary amides with a range of aryl, heteroaryl, and aliphatic amines using potassium tert-butoxide. The reaction proceeds at room temperature under transition-metal-free conditions providing secondary amides in high yields. Moreover, reaction of cyclopropyl amine with tertiary amides proceeds with ring-opening to provide a rapid access to enamides.

Multicomponent synthesis of Ugi-type ceramide analogues and neoglycolipids from lipidic isocyanides

Unique types of ceramide and glycolipid architectures were obtained by means of Ugi reactions incorporating lipidic isocyanides as surrogates of sphingolipids. The multicomponent nature of this approach allowed for a highly efficient assembly process, whe

Rapid and Selective Formylation With Pentafluorophenyl Formate

Pentafluorophenyl formate reacts smoothly with N-nucleophiles under mild conditions to give the N-formyl derivatives, whereas O- and S-nucleophiles remain unaffected even in the presence of a tertiary base.