534-08-7

Usage

Uses

Used in Organic Synthesis:
1,3-diiodopropan-2-ol is used as an intermediate in organic synthesis for its ability to serve as a building block for the creation of other compounds. Its iodine atoms facilitate various chemical reactions, making it a key component in the synthesis process.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1,3-diiodopropan-2-ol is used as a reagent for the synthesis of pharmaceuticals. Its unique structure allows for the development of new drug candidates with potential therapeutic applications.
Used in Fine Chemicals Production:
1,3-diiodopropan-2-ol is also utilized in the production of fine chemicals, where its iodine-containing structure contributes to the creation of specialty chemicals with specific properties and applications.
Used in Derivative Preparation:
This chemical compound is used in the preparation of various derivatives, further expanding its applications across different industries and research areas. Its versatility makes it an important chemical in the field of organic chemistry.

InChI:InChI=1/C3H6I2O/c4-1-3(6)2-5/h3,6H,1-2H2

Upstream product

• 96-23-1 1,3-Dichloro-2-propanol 
• 106-89-8 epichlorohydrin 

Downstream Products

• 5966-51-8 1,3-bis-(dimethylamino)propan-2-ol 
• 1610626-25-9 C₉₃H₁₁₆N₁₂O₁₉ 

Relevant academic research and scientific papers

Expeditious Syntheses to Pharmochemicals 1,3-Dihydroxyacetone, 1,3-Dichloro-, 1,3-Dibromo- And 1,3-Diiodoacetone from Glycerol 1,3-Dichlorohydrin Using Homogenous and Heterogenous Medium

New efficient and reproductive routes to production of 1,3-dihydroxyacetone (1), 1,3-dichloroacetone (6), 1,3-dibromoacetone (7) and 1,3-diiodoacetone (8) from glycerol 1,3-dichlorohydrin (3) were developed. The synthesis of 1 was processed in three steps from glycerol 2 (1,3-selective chlorination of 2 to 3, oxidation of 3 to 6 and subsequent di-hydroxylation) in 51% overall yield. On the other hand, 7 and 8 were produced from 3, via a trans-bromination and trans-iodination, respectively, followed by oxidation and hydroxylation steps, in 38-52% overall yield. It was used homogeneous media with different reagents (HCl/AcOH, pyridinium chlorochromate (PCC), PCC-HIO4) and heterogeneous media with reagents supported on polymer resins such as Amberlyst A26-HCrO4– form, PV-PCC (polyvinyl-pyridinium chlorochromate) and Amberlyst A26-OH– form or reagents supported on alumina such as KI/Al2O3, KBr/Al2O3, in solvent free conditions.

Facile one-pot transformation of carboxylic acid chlorides into 2-substituted allyl alcohols

The reaction of carboxylic acid chlorides (1) with chloromethyl-lithium generated in situ (1:2 molar ratio) in the presence of lithium iodide leads, after hydrolysis, to the corresponding homologated 2-substituted allyl alcohols (2).