53405-13-3Relevant articles and documents
Preparation of a Deuterated Analogue of Tetrahydropapaveroline Suitable for Use as an Internal Standard for G.C./M.S. Analysis of this Alkaloid: Retro Pictet-Spengler Condensation
Clezy, Peter S.,Duncan, Mark W.,Smythe, George A.
, p. 483 - 491 (2007/10/02)
Attempts to prepare deuterated analogues of salsolinol and tetrahydropapaveroline by exchange procedures in D2O have demonstrated that the Pictet-Spengler reaction is a reversible process.Tetrahydropapaveroline can be readily obtained from papaverine by reduction with Zn/HCl followed by demethylation in a process which can conveniently be adopted to produce a (2H3)analogue.