53409-52-2Relevant academic research and scientific papers
Process for preparing 1,2,4-triazole derivatives
-
, (2008/06/13)
1,2,4-TRIAZOLE DERIVATIVES WHICH HAVE PARTICULAR IMPORTANCE AS INTERMEDIATES FOR, E.G., THE PREPARATION OF ACTIVE SUBSTANCES FOR PEST CONTROL, CORRESPONDING TO THE FORMULA STR1 wherein R1 represents an unsubstituted or substituted alkyl, alkenyl, or alkynyl, naphthyl, benzyl, phenylethyl, STR2 or phenylpropyl radical, or a mono or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member, or a substituted phenyl radical, And new processes for the preparation of compounds of the formula STR3 wherein R represents hydrogen, an optionally substituted alkyl, alkenyl or alkynyl radical, an optionally substituted phenyl, naphthyl, benzyl, phenylethyl or phenylpropyl radical, a mono- or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member and/or be substituted by alkyl, or a partially hydrogenated naphthyl radical, which processes are performed by addition to a hydrazine of the formula or to a hydrazone of the formula STR4 wherein R has the above given meaning, R1 represents hydrogen or lower alkyl and R2 represents lower alkyl, of an alkoxy-carbonyl-isothiocyanate of the formula and subsequent closure of the triazole ring in the resulting thiosemicarbazide of the formula STR5 by the splitting-off of an alkanol (alkyl--OH), are disclosed.
