534572-32-2Relevant academic research and scientific papers
C-3′-cyclopropanated taxol analogs: Synthesis, bioassay and biostructural analysis
Liu, Changhui,Tamm, Markus,Noetzel, Marcus W.,Rauch, Karsten,De Meijere, Armin,Schilling, Jennifer K.,Lakdawala, Ami,Snyder, James P.,Bane, Susan L.,Shanker, Natasha,Ravindra, Rudravajhala,Kingston, David G. I.
, p. 3962 - 3972 (2007/10/03)
Ten taxoids with a cyclopropanated side chain were synthesized by coupling a spirocyclopropanated oxazoline-5-carboxylic acid with 7-(triethylsilyl) baccatin III, followed by hydrolytic ring opening and benzoyl migration. The absolute configuration of the
Synthesis and bioactivities of paclitaxel analogs with a cyclopropanated side-chain
Liu, Changhui,Tamm, Markus,N?tzel, Marcus W.,De Meijere, Armin,Schilling, Jennifer K.,Kingston, David G.I.
, p. 2049 - 2052 (2007/10/03)
Four paclitaxel analogs with a cyclopropanated side-chain were synthesized by coupling of the spirocyclopropanated oxazoline-5-carboxylic acid 4 with 7-TES-baccatin III, followed by hydrolytic ring opening and rearrangement. The absolute configuration of
