534591-08-7Relevant academic research and scientific papers
Regio- and stereospecific synthesis of (E)-α-iodoenamide moieties from ynamides through iodotrimethylsilane-mediated hydroiodation
Sato, Akihiro H.,Ohashi, Kazuhiro,Iwasawa, Tetsuo
, p. 1309 - 1311 (2013/03/13)
A facile approach to (E)-α-haloenamide moieties from ynamides using bromo- or iodotrimethylsilane is described. The simple protocol enables a regio- and stereospecific hydrohalogenation of the triple bond in gram-scale and provides a general entry for synthesis of novel enamide analogues.
