534603-34-4Relevant academic research and scientific papers
The synthesis of 2-ketopiperazine acetic acid esters and amides from ethylenediamines with maleates and maleimides
Abelman, Matthew M.,Fisher, Karl J.,Doerffler, Edward M.,Edwards, Paul J.
, p. 1823 - 1826 (2003)
The reaction of substituted ethylenediamines with various fumarates, maleates, and maleimides to form substituted ketopiperazine acetic acid esters and amides was investigated. This method affords a straightforward, high yield approach to a variety of potential peptidomimetics and can yield surprising results with regard to regio- and stereoselectivity.
