5347-94-4

Basic information

• Product Name: 2-{(E)-amino[(2E)-(furan-2-ylmethylidene)hydrazinylidene]methyl}-1-hydroxy-1-oxohydrazinium
• CAS NO: 5347-94-4
• Molecular Formula: C₆H₈N₅O₃
• Molecular Weight: 198.1589
• Mol File: 5347-94-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-{(E)-amino[(2E)-(furan-2-ylmethylidene)hydrazinylidene]methyl}-1-hydroxy-1-oxohydrazinium(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{(E)-amino[(2E)-(furan-2-ylmethylidene)hydrazinylidene]methyl}-1-hydroxy-1-oxohydrazinium(5347-94-4)
• EPA Substance Registry System: 2-{(E)-amino[(2E)-(furan-2-ylmethylidene)hydrazinylidene]methyl}-1-hydroxy-1-oxohydrazinium(5347-94-4)

Safety Data

• Hazardous Substances Data: 5347-94-4(Hazardous Substances Data)

Usage

Amino group

Contains a nitrogen atom bonded to two hydrogen atoms and one carbon atom

Furan ring

Consists of a five-membered ring with four carbons and one oxygen

Hydrazine group

Contains two nitrogen atoms bonded together

Hydroxy functionality

Contains a hydroxyl group (-OH) which can act as a hydrogen bond donor and acceptor

Oxo functionality

Contains a carbonyl group (C=O) which can participate in various chemical reactions

Methylidene derivative

Contains a methyl group (-CH2-) bonded to a carbon atom

Hydrazinylidene group

Contains a hydrazinylidene group which is a derivative of hydrazine

Potential applications

Pharmaceuticals, organic synthesis, drug development

Further research needed

To fully understand the properties and potential uses of the compound.

Upstream product

• 58371-76-9 3-(furan-2-yl)-2-nitro-1-phenylprop-2-en-1-one 
• 18264-75-0 1-amino-2-nitroguanidine 
• 73604-88-3 1-nitro-2-(2-furyl)-1-ethoxycarbonylethene 
• 98-01-1 furfural 
• 18264-75-0 3-amino-1-nitroguanidine 

Relevant articles and documents

Synthesis, insecticidal and fungicidal activities of methyl 2-(methoxyimino)-2-(2-((1-(N′-nitrocarbamimidoyl)-2-hydrocarbylidene-hydrazinyl)methyl)phenyl)acetates

N′-Nitro-2-hydrocarbylidenehydrazinecarboximidamides and methoxyacrylates are two types of important agrochemicals. By combining their key fragments into one framework, a series of the title compounds was designed and synthesized. Some of these compounds have shown excellent insecticidal activities for aphides, for example, the LC50 values of compounds 6-06, 6-11 and 6-19 against M. perslcae and H. amygdale were found to be 1.9/14.4, 13.4/1.5 and 0.3/38.4 mg L-1 respectively. They were also effective against the mycelium growth of B. cinerea in vitro. Compound 6-04 could control (～100%) cucumber anthrax and rice blast at 100 mg L-1 in vivo, and inhibit the spore germination (～100%) of vegetable gray mold at 6.25 mg L-1. These compounds could be considered as potential insecticidal or fungicidal candidates for crop protection. The results of structure-activity relationship (SAR) studies are discussed.

Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)ethenes

Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)-ethenes proceed via initial formation the aza-Michael product, are accompanied by liberation of nitroacetic ester (or nitroacetophenone), and result in N-aryl(het

N ′-nitro-2-hydrocarbylidenehydrazinecarboximidamides: Design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships

A novel series of acyclic imine-substituted nitenpyram analogues were designed and synthesized from nitroaminoguanidine, and their structures were confirmed using X-ray diffraction crystallography. Preliminary bioassays showed that the target molecules exhibited good activities against aphids in laboratory (Myzus persicae Sulzer) and field trials (M. persicae Sulzer and Brevicoryne brassicae Linnaeus). Comparative molecular field analysis and comparative molecular similarity indices analysis were employed to develop a three-dimensional quantitative structure-activity relationship model that describes the insecticidal activity of 21 neonicotinoid derivatives. Simple synthesis, low cost, and good insecticidal activity have made this series of compounds become very promising candidates for future commercial pesticides.