5347-98-8

Usage

Backbone

Hydrazine

Functional Groups

Amino Group (NH2): Provides basic properties and potential reactivity in organic synthesis.
Nitro Group (NO2): Suggests potential antimicrobial or antiparasitic properties.
Hydroxy Group (OH): Adds hydrophilic character and potential for hydrogen bonding.

Moieties

Benzylidene Moiety: Contributes to the overall structure and reactivity.
Oxohydrazinium Moiety: Provides additional reactivity and potential interactions.

Reactivity

Highly reactive, indicating potential for various chemical reactions.

Potential Applications

Organic Synthesis: Due to its multiple functional groups, it could be used as a building block in organic synthesis.
Pharmaceutical Research: Potential applications in drug discovery and development due to its reactivity and diverse functional groups.
Antimicrobial/Antiparasitic Properties: Presence of the nitro group suggests potential for antimicrobial or antiparasitic activity.
Treatment of Tuberculosis or Cancer: The hydrazine moiety may make it a candidate for research in treating tuberculosis or cancer.

Research Needs

Further research is necessary to fully understand its properties and potential uses.

Upstream product

• 18264-75-0 1-amino-2-nitroguanidine 
• 552-89-6 2-nitro-benzaldehyde 
• 18264-75-0 3-amino-1-nitroguanidine 

Downstream Products

• 1227850-16-9 2-(2'-nitrobenzylidene)-N-propyl-N'-nitrohydrozinecarboximidamides 
• 1376342-39-0 C₁₄H₁₂ClN₇O₄ 

Relevant academic research and scientific papers

N ′-nitro-2-hydrocarbylidenehydrazinecarboximidamides: Design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships

A novel series of acyclic imine-substituted nitenpyram analogues were designed and synthesized from nitroaminoguanidine, and their structures were confirmed using X-ray diffraction crystallography. Preliminary bioassays showed that the target molecules exhibited good activities against aphids in laboratory (Myzus persicae Sulzer) and field trials (M. persicae Sulzer and Brevicoryne brassicae Linnaeus). Comparative molecular field analysis and comparative molecular similarity indices analysis were employed to develop a three-dimensional quantitative structure-activity relationship model that describes the insecticidal activity of 21 neonicotinoid derivatives. Simple synthesis, low cost, and good insecticidal activity have made this series of compounds become very promising candidates for future commercial pesticides.

HYDROCARBYLIDENE NITROHYDROZINECARBOXIMIDAMIDES AND A METHOD FOR MAKING THE SAME, AS WELL AS THEIR USES AS AN INSECTICIDE

The present invention discloses hydrocarbylidene nitrohydrozinecarboximidamides and the use thereof as well as a method for making the same. The structural general formula of the compounds are shown in formula I, wherein, R1 is C1-C10 saturated and/or unsaturated aliphatic hydrocarbonyl, benzyl, substituted benzyl, halogenated picolyl, halogenated thiazolyl methyl, tetrahydrofuryl methyl or oxazolyl methyl; R2 is hydrogen, C1-C5 saturated and/or unsaturated aliphatic hydrocarbonyl, phenyl, substituted phenyl, pyridyl or substituted pyridyl; R3 is hydrogen, C1-C10 saturated and/or unsaturated aliphatic hydrocarbonyl, furyl, phenyl, substituted phenyl, benzyl or substituted benzyl. The tests of insecticidal activity show that the hydrocarbylidene nitrohydrozinecarboximidamides shown by formula (I) have high preventive efficiency against insect pests of plants, such as aphid, plant hopper, cotton bollworm, asparagus caterpillar, and the like, and can be used as plant insecticides.

CONDENSED AMINO NITROGUANIDINE COMPOUNDS, SYNTHESIS AND USE AS BOTANICAL INSECTICIDES THEREOF

The present invention discloses hydrocarbylidene nitrohydrozinecarboximidamides and the use thereof as well as a method for making the same. The structural general formula of the compounds are shown in formula I, wherein, R1 is C1 - C10 saturated and/or unsaturated aliphatic hydrocarbonyl, benzyl, substituted benzyl, halogenated picolyl, halogenated thiazolyl methyl, tetrahydrofuryl methyl or oxazolyl methyl; R2 is hydrogen, C1 - C5 saturated and/or unsaturated aliphatic hydrocarbonyl, phenyl, substituted phenyl, pyridyl or substituted pyridyl; R3 is hydrogen, C1 - C10 saturated and/or unsaturated aliphatic hydrocarbonyl, furyl, phenyl, substituted phenyl, benzyl or substituted benzyl. The tests of insecticidal activity show that the hydrocarbylidene nitrohydrozinecarboximidamides shown by formula (I) have high preventive efficiency against insect pests of plants, such as aphid, plant hopper, cotton bollworm, asparagus caterpillar, and the like, and can be used as plant insecticides.