5347-99-9Relevant academic research and scientific papers
Synthesis and insecticidal activity of novel 1,2,4-triazole derivatives containing trifluoroacetyl moieties
Li, Jia-Qi,Liu, Min,Qin, Zhaohai,Tang, Xianjun,Xiao, Yumei,Zhao, Fenghai
, (2021/10/01)
A series of compounds containing trifluoroacetyl groups were synthesized, and their insecticidal activity against Nilaparvata lugens and Aphis craccivora was evaluated. The compound structure was identified by NMR, HRMS, and single-crystal diffraction. The bioassay results indicated that compound 4-1 (R1 is chloropyridine, R2 is H), 4-2 (R1 is chlorothiazole, R2 is H) and 4-19 (R1 is benzyl, R2 is isopropyl) had the best activity against Nilaparvata lugens (93.5%, 94.1% and 95.5%) at 100?mg/L concentration. The effect of different substituents of R1 or R2 on the activity was studied through the structure–activity relationship. Molecular docking of compounds 4-1 and 4-2 was discussed. Graphic abstract: [Figure not available: see fulltext.].
Synthesis, insecticidal and fungicidal activities of methyl 2-(methoxyimino)-2-(2-((1-(N′-nitrocarbamimidoyl)-2-hydrocarbylidene-hydrazinyl)methyl)phenyl)acetates
Yuan, Xiaoyong,Jia, Changqing,Ma, Yongqiang,Yang, Dongyan,Rui, Changhui,Qin, Zhaohai
, p. 19916 - 19922 (2016/03/04)
N′-Nitro-2-hydrocarbylidenehydrazinecarboximidamides and methoxyacrylates are two types of important agrochemicals. By combining their key fragments into one framework, a series of the title compounds was designed and synthesized. Some of these compounds have shown excellent insecticidal activities for aphides, for example, the LC50 values of compounds 6-06, 6-11 and 6-19 against M. perslcae and H. amygdale were found to be 1.9/14.4, 13.4/1.5 and 0.3/38.4 mg L-1 respectively. They were also effective against the mycelium growth of B. cinerea in vitro. Compound 6-04 could control (～100%) cucumber anthrax and rice blast at 100 mg L-1 in vivo, and inhibit the spore germination (～100%) of vegetable gray mold at 6.25 mg L-1. These compounds could be considered as potential insecticidal or fungicidal candidates for crop protection. The results of structure-activity relationship (SAR) studies are discussed.
Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)ethenes
Efimova,Ozerova,Novikova,Baichurin,Berestovitskaya
, p. 1496 - 1499 (2015/01/09)
Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)-ethenes proceed via initial formation the aza-Michael product, are accompanied by liberation of nitroacetic ester (or nitroacetophenone), and result in N-aryl(het
Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)ethenes
Efimova,Ozerova,Novikova,Baichurin,Berestovitskaya
, p. 1496 - 1499 (2015/02/19)
Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)-ethenes proceed via initial formation the aza-Michael product, are accompanied by liberation of nitroacetic ester (or nitroacetophenone), and result in N-aryl(het
β-Nitro-and β-bromo-β-nitrostyrenes in the reactions with aminonitroguanidine
Efimova,Ozerova,Belik,Novikova,Berestovitskaya
, p. 1409 - 1415 (2013/01/15)
The conditions for the reactions of β-nitro- and β-bromo-β- nitrostyrenes with 1-amino-2- nitroguanidine resulting in the amination products, 1-nitro- and 1-bromo-1-nitro-2-aryl-2-(2-nitroguanidinoamino) ethanes, were found. Under the action of the basic
