53471-74-2Relevant academic research and scientific papers
New hepato protective agents. I. Maleopimaric acid 4α carboxamides
Danswan,Ramm,Taylor
, p. 2188 - 2189 (2007/10/09)
A number of amide derivatives of maleopimaric acid were synthesized and preliminary results on their protective activity against galactosamine induced liver damage in the rat are described. The compounds were found to display the highest level of protective activity producing significant lowering of serum GOT and GPT levels at a daily dose of 250-300 mg/kg. The LD50 of these compounds was typically in excess of 2000 mg/kg.
