53475-18-6

Usage

Uses

Used in Organic Synthesis:
1-(methylsulfanyl)-1-phenylpropan-2-one is used as a reagent in organic synthesis for its ability to react with various compounds to form new chemical entities.
Used in Food Industry:
1-(methylsulfanyl)-1-phenylpropan-2-one is used as a flavoring agent in the food industry for its unique taste and aroma.
Used in Pharmaceutical Production:
1-(methylsulfanyl)-1-phenylpropan-2-one is used as a key intermediate in the production of pharmaceuticals for its role in the synthesis of various drug compounds.
Used in Fragrance Industry:
1-(methylsulfanyl)-1-phenylpropan-2-one is used as a key intermediate in the production of fragrances for its ability to contribute to the overall scent profile of various perfumes and scented products.
Used in Chemical Compounds Production:
1-(methylsulfanyl)-1-phenylpropan-2-one is used as a key intermediate in the production of other chemical compounds for its versatility in chemical reactions and its ability to form new compounds with desired properties.

Upstream product

• 101743-36-6 2,5-dimethyl-3,6-diphenyl-[1,4]dithiane-2,5-diol 
• 77-78-1 dimethyl sulfate 
• 74-93-1 methylthiol 
• 4773-35-7 1-chloro-1-phenylpropan-2-one 
• 5756-24-1 dimethyl tetrasulfide 
• 103-79-7 1-phenyl-acetone 
• 56870-03-2 1-chloro-1-methylsulfanyl-propan-2-one 
• 71-43-2 benzene 
• 873-66-5 1-propenylbenzene 
• 5799-67-7 dimethyl(methylthio)sulfonium tetrafluoroborate 
• 5813-48-9 Methanesulfenyl chloride 
• 43108-63-0 1-phenyl-2-trimethylsiloxy-1-propene 

Downstream Products

• 103-79-7 1-phenyl-acetone 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 29548-91-2 1-phenyl-1,1-difluoropropan-2-one 

Relevant academic research and scientific papers

Syntheses of Arylacetone and Arylacetonitrile by Friedel-Crafts Reaction with α-Chloro-α-(methylthio)-substituted Acetone and Acetonitrile

Novel preparative methods for arylacetone and arylacetonitrile are described.Friedel-Crafts reactions of aromatic compounds with α-chloro-α-(methylthio)acetone (4) and α-chloro-α-(methylthio)acetonitrile (7) in the presence of Lewis acid afforded α-(methylthio)arylacetone (5) and α-(methylthio)arylacetonitrile (8), respectively.Compounds (5) and (8) were converted into the corresponding arylacetone (6) and arylacetonitrile (9) by reduction with zinc dust in acetic acid.Keywords: Friedel-Crafts reaction with α-chloro-α-(methylthio)acetone; Friedel-Crafts reaction with α-chloro-α-(methylthio)acetonitrile; α-(methylthio)arylacetone; α-(methylthio)arylacetonitrile; arylacetone; arylacetonitrile; reductive desulfurization; zinc dust-acetic acid

Introduction of α-(acyl) methylthiomethyl group into the aromatic ring by Friedel-Crafts reaction

Friedel-Crafts α-(acyl)methylthiomethylations of aromatic compounds with α-ethoxycarbonyl, -acetyl, -benzoyl, and -cyano-α-(methylthio)methyl chlorides are described. The resulted products are easily converted to acylmethylated aromatics such as phenylacetate and phenylacetone by reductive desulfurization.