53483-40-2Relevant academic research and scientific papers
Diethyl zinc catalyzed diastereoselective addition of ketenes to (S)-(+)-3-hydroxytetrahydrofuran
Tandon, Vishnu K.
, p. 5985 - 5987 (2007/10/03)
The reaction of (S)-(+)-3-hydroxytetrahydrofuran with phenyl methyl ketene in presence of n-BuLi and Et2Zn results in the formation of the diastereomeric esters (SS+SR) with a high degree of diastereoselectivity (98:2).
Kinetic Resolution of Racemic Carboxylic Acids and Alcohols with Homochiral Alcohols and Carboxylic Acids, Respectively, and the Mukaiyama or Palomo Reagents
Mazon, Angel,Najera, Carmen,Yus, Miguel,Heumann, Andreas
, p. 1455 - 1466 (2007/10/02)
The Mukaiyama and Palomo reagents have been used for the kinetic resolution of racemic carboxylic acids or alcohols with homochiral alcohols or carboxylic acids, respectively, in the presence of triethylamine.Thus, enantiomerically enriched carboxylic acids (e.e.68percent), alcohols (e.e.41percent) or diastereoisomerically enriched esters (d.e.84percent) are obtained.
