53494-57-8 Usage
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
(S)-1-Amino-3-chloro-2-propanol is utilized as a fundamental building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable component in the development of new drugs and agricultural chemicals.
Used as a Chiral Resolution Reagent:
In the field of chemistry, (S)-1-Amino-3-chloro-2-propanol serves as a chiral resolution reagent. This application is crucial for separating enantiomers, which are molecules that are mirror images of each other but may have different biological activities.
Used in Surfactant and Corrosion Inhibitor Production:
(S)-1-Amino-3-chloro-2-propanol is employed as a precursor in the production of surfactants and corrosion inhibitors. Its role in these industries is essential for creating effective products that can be used in various applications, such as cleaning agents and protective coatings.
Used in Polymer and Plastics Manufacturing:
Furthermore, (S)-1-Amino-3-chloro-2-propanol has applications in the manufacturing of polymers and plastics. Its incorporation into these materials can enhance their properties, such as strength, durability, and resistance to environmental factors.
Check Digit Verification of cas no
The CAS Registry Mumber 53494-57-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,4,9 and 4 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 53494-57:
(7*5)+(6*3)+(5*4)+(4*9)+(3*4)+(2*5)+(1*7)=138
138 % 10 = 8
So 53494-57-8 is a valid CAS Registry Number.
InChI:InChI=1/C3H8ClNO/c4-1-3(6)2-5/h3,6H,1-2,5H2/t3-/m1/s1
53494-57-8Relevant articles and documents
Environment-friendly synthesis method of linezolid and intermediate thereof
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Paragraph 0043; 0044; 0045, (2018/11/22)
The invention relates to a more environment-friendly synthesis method of linezolid and a key intermediate thereof. The more environment-friendly synthesis method is characterized in that the key intermediate of linezolid is prepared through the steps of hydroxyl protection, carboxyl reduction, hydroxyl halogenation, ring closing, halogenation after hydroxyl deprotection, ring opening and the likeby taking a natural chiral product L-serine as an initial raw material. According to the more environment-friendly synthesis method provided by the invention, a chiral center is introduced by adoptingthe natural chiral product, the reaction yield is high, the technological operation is simple, the product purity is high, and the synthesis method is more environment-friendly and is suitable for industrial production.
Dynamic kinetic resolution of epichlorohydrin via enantioselective catalytic ring opening with TMSN3. Practical synthesis of aryl oxazolidinone antibacterial agents
Schaus, Scott E.,Jacobsen, Eric N.
, p. 7937 - 7940 (2007/10/03)
The dynamic kinetic resolution of racemic epichlorohydrin has been achieved via enantioselective asymmetric ring opening with TMSN3 catalyzed by the (salen)Cr(III)N3 complex 1. The resulting 3-azido-1-chloro-2-trimethylsiloxypropane product was obtained in high enantiomeric purity and incorporated into the synthesis of U-100592, a representative from a class of highly-promising aryl oxazolidinone antibacterial agents.
