53524-88-2

Basic information

• Product Name: NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE
• Synonyms: NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE;2-(3-NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE
• CAS NO: 53524-88-2
• Molecular Formula: C₁₃H₁₀N₂O₂
• Molecular Weight: 226.23
• Mol File: 53524-88-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 252-255°C
• Appearance: /
• Density: 1.346g/cm³
• Refractive Index: 1.725
• CAS DataBase Reference: NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE(53524-88-2)
• EPA Substance Registry System: NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE(53524-88-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 53524-88-2(Hazardous Substances Data)

Usage

General Description

Naphtho[2,1-b]furan-2-carbohydrazide is a synthetic organic compound that belongs to the class of chemical entities known as furanoids. These comprise a group of compounds featuring furan, a 5-membered aromatic ring with four carbon atoms and one oxygen atom, usually having two double bonds. The chemical group, carbohydrazide, is coupled with naphtho-furan, forming intricate structures with wide applications in chemical research and pharmacological studies. More specific data pertaining to its physical properties, exact applications and safety information are often proprietary and not publicly available due to its importance in research and potential commercial applications.

InChI:InChI=1/C13H10N2O2/c14-15-13(16)12-7-10-9-4-2-1-3-8(9)5-6-11(10)17-12/h1-7H,14H2,(H,15,16)

Upstream product

• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 
• 32730-03-3 2-carbetossinafto<2,1-b>furano 
• 5656-67-7 acide naphtho<2,1-b>furanne carboxilique 

Downstream Products

• 443993-34-8 naphtho[2,1-b]furan-2-carboxylic acid (4-nitro-benzylidene)-hydrazide 
• 496919-77-8 naphtho[2,1-b]furan-2-carboxylic acid (3-chloro-benzylidene)-hydrazide 
• 444009-57-8 naphtho[2,1-b]furan-2-carboxylic acid (3-hydroxy-benzylidene)-hydrazide 
• 1148119-88-3 4-anilino-5-naphtho[2,1-b]furan-2-yl-4H-[1,2,4]-triazole-3-thiol 
• 941670-16-2 C₂₄H₁₆ClN₃O₂ 
• 371135-20-5 STK899704 
• 496915-67-4 naphtho[2,1-b]furan-2-carboxylic acid (3-nitro-benzylidene)-hydrazide 
• 496915-63-0 naphtho[2,1-b]furan-2-carboxylic acid (4-chloro-benzylidene)-hydrazide 
• 496915-68-5 naphtho[2,3-a]furan-2-carboxy-[2'-hydroxyphenyl]carbohydrazone 

Relevant articles and documents

Rapid and Selective Detection of Cyanide Anion by Enhanced Fluorescent Emission and Colorimetric Color Changes at Micromole Levels in Aqueous Medium

One main source of cyanide (CN?) exposure for mammals is through the plant consumption; thus, the sensitive and selective cyanide detection in plant tissue is a significant and urgent work. Here, a simple sensor N′-(2,4-dihydroxybenzylidene)naphtha[2,1-b]furan-2-carbohydrazide (Q1-3) was designed and synthesized for selective and sensitive dual-channel detection of cyanide in aqueous medium (DMSO/H2O, 1:9, v/v). Acylhydrazone and phenolic hydroxyl groups on Q1-3 are the recognition sites, and naphthofuran group is the signal report group. The intramolecular charge transfer between the benzene group and naphthofuran group was impeded because of the electron-withdrawing groups (hydroxyl) on sensor Q1-3. Interestingly, the sensor Q1-3 exhibited an intramolecular charge transfer absorption band at 400?nm and emission band at 500?nm, respectively, directly realizing an “OFF–ON” response after the deprotonation process induced by cyanide anions in aqueous medium (DMSO/H2O, 1:9, v/v). Notably, this sensor was successfully applied to detect cyanide anions in food samples, which proves a very simple and selective platform for on-site monitoring of cyanide in agriculture samples. In addition, the test strips and silica gel plates based on Q1-3 were also fabricated, which could act as test kits and silica gel plates for convenient and efficient detection of cyanide anions.

A highly selective PET-based chemosensor for instant detecting of Zn 2+

A simple Zn2+-selective chemosensor system based on acylhydrazone was designed and synthesized, which could detect Zn2+ ions in aqueous solution with high selectivity and sensitivity over a wide pH range by the mechanism of photo-ind