53544-07-3Relevant academic research and scientific papers
Regioselective synthesis of a potent Src kinase inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8-(2-morpholin-4-ylethoxy) benzo[g]quinoline-3-carbonitrile
Berger, Dan M.,Birnberg, Gary,DeMorin, Frenel,Dutia, Minu,Powell, Dennis,Wang, Yanong D.
, p. 1712 - 1716 (2007/10/03)
The regioselective synthesis of compound 3, a potent Src kinase inhibitor is described. A key step in this synthesis is the regioselective thermal rearrangement of a substituted benzocyclobutene to provide a 2,3,6,7-tetrasubstituted naphthalene. An effici
Method for the regioselective preparation of substituted benzo[g]quinoline3-carbonitriles and benzo[g]quinazolines
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, (2008/06/13)
This invention relates to a method for the regioselective synthesis of 4,6,7,8-substituted benzo[g]quinoline-3-carbonitriles and 4,6,7,8-substituted benzo[g]quinazolines as well as intermediates thereof. The compounds derived from this invention are usefu
Tricyclic protein kinase inhibitors
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, (2008/06/13)
This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyro sine kinase and are antiproliferative agents.
