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Usage

Uses

Used in Automotive Industry:
HALS 292 is used as a UV stabilizer for automotive parts to protect them from degradation and discoloration caused by long-term exposure to sunlight. This helps maintain the integrity and appearance of the parts, ensuring their durability and longevity.
Used in Building Materials:
HALS 292 is used as a UV stabilizer in building materials to provide long-term protection against the harmful effects of UV light. This helps maintain the structural integrity and appearance of the materials, ensuring their durability and longevity.
Used in Agricultural Films:
HALS 292 is used as a UV stabilizer in agricultural films to protect them from degradation and discoloration caused by exposure to sunlight. This helps maintain the effectiveness and longevity of the films, ensuring their ability to protect crops and promote growth.
Used for Thermal Stability and Processing Benefits:
HALS 292 provides thermal stability and processing benefits in various industries, making it a versatile and valuable additive. Its ability to absorb and dissipate UV radiation, along with its thermal stability, makes it an essential component in the production of polymers and plastics.

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 1620-98-0 3,5-di-t-butyl-4-hydroxybenzaldehyde 

Relevant academic research and scientific papers

2-Arylidene-1-indandiones as Pleiotropic Agents with Antioxidant and Inhibitory Enzymes Activities ?

Indandiones are a relatively new group of compounds presenting a wide range of biological activities. The synthesis of these compounds was performed via a Knoevenagel reaction between an aldehyde and 1,3-indandione and were obtained with a yield up to 54%

Chemical uncouplers for the treatment of obesity

This invention relates to chemical uncouplers with a broader safety window making the use of them in treating obesity and, consequently, in the treatment of obesity related diseases and conditions such as atherosclerosis, hypertension, diabetes, especially type 2 diabetes (NIDDM (non-insulin dependent diabetes mellitus)), impaired glucose tolerance, dyslipidemia, coronary heart disease, gallbladder disease, osteoarthritis and various types of cancer such as endometrial, breast, prostate and colon cancers and the risk for premature death as well as other conditions, such as diseases and disorders, which conditions are improved by an increase in mitochondrial respiration, more attractive.

TX-1123: An antitumor 2-hydroxyarylidene-4-cyclopentene-1,3-dione as a protein tyrosine kinase inhibitor having low mitochondrial toxicity

A series of 2-hydroxyarylidene-4-cyclopentene-1,3-diones were designed, synthesized, and evaluated with respect to protein tyrosine kinase (PTK) inhibition, mitochondrial toxicity, and antitumor activity. Our results show that the cyclopentenedione-derived TX-1123 is a more potent antitumor tyrphostin and also shows lower mitochondrial toxicity than the malononitrile-derived AG17, a potent antitumor tyrphostin. The O-methylation product of TX-1123 (TX-1925) retained its tyrphostin-like properties, including mitochondrial toxicity and antitumor activities. However, the methylation product of AG17 (TX-1927) retained its tyrphostin-like antitumor activities, but lost its mitochondrial toxicity. Our comprehensive evaluation of these agents with respect to protein tyrosine inase inhibition, mitochondrial inhibition, antitumor activity, and hepatotoxicity demonstrates that PTK inhibitors TX-1123 and TX-1925 are more promising candidates for antitumor agents than tyrphostin AG17. Copyright

Synthesis and anti-inflammatory activity of (3,5-di-tert-butyl-4-hydroxybenzylidene) cyclanones and related compounds

Some (3,5-di-tert-butyl-4-hydroxybenzylidene) cyclanones were synthesized and evaluated for anti-inflammatory activity in carragenin-induced rat paw edema assay. These compounds are slightly less active than phenylbutazone. Their inhibitory effects in vit