53580-62-4

Usage

Uses

Used in Fragrance Industry:
3-(2-Hydroxy-phenyl)-propionaldehyde is used as a fragrance ingredient for its ability to add a pleasant and lasting scent to various personal care products. It is valued for its floral, green, and slightly sweet aroma, which can significantly enhance the overall scent profile of perfumes, lotions, and shampoos.
Used in Cosmetic Industry:
In the cosmetic industry, 3-HPA is used as an additive in a variety of products to provide a desirable scent. Its role in enhancing the fragrance of other compounds makes it a popular choice for improving the sensory experience of cosmetics, thereby increasing their appeal to consumers.
Used in Research:
3-(2-Hydroxy-phenyl)-propionaldehyde is also used in research settings as a precursor for the synthesis of bioactive compounds. Its chemical properties make it a valuable component in the development of new substances with potential applications in various fields, including pharmaceuticals and materials science.
Used in Personal Care Products:
3-HPA is incorporated into personal care products such as perfumes, lotions, and shampoos to add a unique and appealing scent. Its ability to stabilize the fragrance of other compounds ensures that the scent remains consistent and long-lasting, enhancing the overall consumer experience.

InChI:InChI=1/C9H10O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-2,4,6-7,11H,3,5H2

Upstream product

• 132652-41-6 3-[2-((E)-4-Bromo-but-2-enyloxy)-phenyl]-propionaldehyde 
• 92799-73-0 1-indanyl hydroperoxide 
• 496-11-7 INDANE 
• 60125-23-7 (E)-3-(2-hydroxyphenyl)propenal 

Relevant academic research and scientific papers

Substrate-Controlled, One-Pot Synthesis: Access to Chiral Chroman-2-one and Polycyclic Derivatives

Based on the appropriate choice of electrophiles, one-pot, multicomponent, enantioselective domino reactions have been realized which contain a five-step sequence and provide highly efficient access to potentially bioactive chroman-2-one derivatives as a single diastereoisomer with excellent enantioselectivities and in high yields. This new strategy could significantly improve the previous protocol by directly starting from commercial 2-hydroxybenzaldehydes rather than preformed lactols, which have to be synthesized in several additional steps. (Chemical Equation Presented).

CYCLIC PEROXIDE OXIDATION OF AROMATIC COMPOUND PRODUCTION AND USE THEREOF

The present invention provides a method for converting an aromatic hydrocarbon to a phenol by providing an aromatic hydrocarbon comprising one or more aromatic C-H bonds and one or more activated C-H bonds in a solvent; adding a phthaloyl peroxide to the solvent; converting the phthaloyl peroxide to a di-radical; contacting the di-radical with the one or more aromatic C-H bonds; oxidizing selectively one of the one or more aromatic C-H bonds in preference to the one or more activated C-H bonds; adding a hydroxyl group to the one of the one or more aromatic C-H bonds to form one or more phenols; and purifying the one or more phenols.

Synthesis of aromatic aldehydes by aerobic oxidation of hydroaromatic compounds and diarylalkanes using N-hydroxyphthalimide (NHPI) as a key catalyst

Aerobic oxidation of hydroaromatic compounds and diarylalkanes by N-hydroxyphthalimide (NHPI) under mild conditions afforded the corresponding hydroperoxides in high selectivity. Treatment of the resulting hydroperoxides with sulfuric acid followed by neutralization by a base resulted in phenol and aromatic aldehydes in high selectivity. This method provides a convenient synthetic route to aldehydes involving an aromatic moiety.

7-PHENYL-ISOQUINOLINE-5-SULFONYLAMINO DERIVATIVES AS INHIBITORS OF AKT (PROTEINKINASE B)

The present invention relates to compounds Formula (I) as inhibitors of AKT activity, which are useful for the treatment of susceptible neoplasms and viral infections.

HETERO-ATOM SUBSTITUTED CHROMIUM ALLYLS: SYNTHETIC STUDIES ON NEOCARZINOSTATIN CHROMOPHORE ANALOGUES

The preparation and reactions of hetero-atom substituted chromium allyls derived from 7a, 7b, 12, and 15 are described in connection with studies on the synthesis of neocarzinostatin analogues.